The American Psychiatric Publishing Textbook of Psychopharmacology

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American Psychiatric Pub, 2009 - Medical - 1616 pages
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Its last edition hailed as "an essential volume for psychiatry residents as well as clinicians" (Journal of Psychiatric Practice), The American Psychiatric Publishing Textbook of Psychopharmacology is now updated to keep you abreast of the latest research and trends in the field. Covering both basic science and clinical practice, this new edition draws on the talents of 53 new contributors -- with the total increased from 139 to 158 -- to guarantee fresh, authoritative perspectives on advances in psychiatric drug therapy.

Introductory chapters provide a theoretical grounding in clinical applications, with coverage ranging from neurotransmitters to clinical trial design. The "Classes of Psychiatric Treatment" section is a virtual pharmacopoeia, with chapters devoted to specific agents. It presents information by class of drug, and for each agent provides data on indications, side effects, interactions, and more -- including drugs likely to become available in the near future. Chapters in the "Clinical Psychobiology and Psychiatric Syndromes" section review the neurological underpinnings of specific disorders, providing a context for understanding psychopharmacological approaches to treatment. Coverage of those treatments encompasses state-of-the-art approaches to psychiatric disorders; specific patient populations, such as children and pregnant women; difficult-to-manage conditions like insomnia; and specific guidance on drug selection and prescription. Among the features of the fourth edition are the following ? A new chapter on genomics and genetics covers basic methodologies and concepts to help you interpret the avalanche of data appearing in the human neuroscience literature.? Expanded chapters address newly approved agents, including the antidepressant desvenlafaxine, the antipsychotic paliperidone, and the anticonvulsant pregabalin.? A new chapter on the neurobiology of childhood disorders considers data relating to pervasive developmental disorders, psychoses, learning disorders, disruptive behavior disorder/ADHD, bipolar disorder, major depressive disorder, obsessive-compulsive disorder/Tourette's syndrome, PTSD, and pediatric anxiety disorders.? A new chapter on treatment of chronic pain syndromes discusses major classes of medications as they relate to pain management and covers prevalent disorders -- such as fibromyalgia and osteoarthritis -- in which this is a priority and for which evidence-based therapy is available.? A new, comprehensive review of ethical considerations in psychopharmacological treatment and research addresses such concerns as high-risk pharmacotherapy, long-acting medications, and off-label prescribing.

Solidly established as an authoritative and comprehensive source, the new edition of this new edition of The American Psychiatric Publishing Textbook of Psychopharmacology is even more indispensable for clinicians and researchers alike.

 

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Contents

Neurotransmitters Receptors Signal Transduction and Second Messengers in Psychiatric Disorders
3
Basic Principles of Molecular Biology and Genomics
59
Genetics and Genomics
81
Chemical Neuroanatomy of the Primate Brain
105
Electrophysiology
135
Animal Models
153
Psychoneuroendocrinology
161
Principles of Pharmacokinetics and Pharmacodynamics
181
Valproate
719
Carbamazepine and Oxcarbazepine
735
Gabapentin and Pregabalin
767
Lamotrigine
779
Topiramate
795
Other Agents
809
Cognitive Enhancers
811
SedativeHypnotics
821

BrainImmune System Interactions Relevance to the Pathophysiology and Treatment of Neuropsychiatric Disorders
201
Brain Imaging in Psychopharmacology
221
Statistics Placebo Response and Clinical Trial Design in Psychopharmacology
243
Classes of Psychiatric Treatments Animal and Human Pharmacology
259
Antidepressants and Anxiolytics
261
Tricyclic and Tetracyclic Drugs
263
Fluoxetine
289
Sertraline
307
Paroxetine
321
Fluvoxamine
353
Citalopram and SCitalopram
363
Monoamine Oxidase Inhibitors
389
Trazodone and Nefazodone
403
Bupropion
415
Mirtazapine
429
Venlafaxine and Desvenlafaxine
439
Duloxetine and Milnacipran
453
Benzodiazepines
465
Buspirone and Gepirone
487
Putative NewGeneration Antidepressants
503
Antipsychotics
531
Classic Antipsychotic Medications
533
Clozapine
555
Olanzapine
573
Quetiapine
599
Aripiprazole
613
Risperidone and Paliperidone
627
Ziprasidone
641
Drugs to Treat Extrapyramidal Side Effects
669
Drugs for Treatment of Bipolar Disorder
695
Lithium
697
Psychostimulants and WakefulnessPromoting Agents
843
Electroconvulsive Therapy
861
Clinical Psychobiology and Psychiatric Syndromes
901
Neurobiology of Mood Disorders
903
Neurobiology of Schizophrenia
945
Neurobiology of Anxiety Disorders
965
Neurobiology of Alzheimers Disease
987
Neurobiology of Substance Abuse and Addiction
1007
Neurobiology of Eating Disorders
1027
Neurobiology of Personality Disorders
1045
Neurobiology of Childhood Disorders
1061
Psychopharmacological Treatment
1079
Treatment of Depression
1081
Treatment of Bipolar Disorder
1113
Treatment of Schizophrenia
1135
Treatment of Anxiety Disorders
1171
Treatment of Agitation and Aggression in the Elderly
1201
Treatment of SubstanceRelated Disorders
1213
Treatment of Eating Disorders
1231
Treatment of Insomnia
1241
Treatment of Personality Disorders
1267
Treatment of Psychiatric Emergencies
1287
Treatment of Child and Adolescent Disorders
1309
Psychopharmacology During Pregnancy and Lactation
1373
Treatment During Late Life
1413
Treatment of Chronic Pain Syndromes
1441
Ethical Issues
1475
Ethical Considerations in Psychopharmacological Treatment and Research
1477
Index
1497
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About the author (2009)

Alan F. Schatzberg, M.D., is Kenneth T. Norris Jr. Professor and Chair of the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine in Stanford, California.

Charles B. Nemeroff, M.D., Ph.D., is Reunette W. Harris Professor in the Department of Psychiatry and Behavioral Sciences at Emory University School of Medicine in Atlanta, Georgia.

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