A Cyclopaedia of Drug Pathogenesy, Volume 2

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Gould, 1888
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Page 379 - ... if he should be reading at the time, he will suddenly find the occupation fatiguing, and, very soon afterwards, it may be impossible ; and he will be glad to close the eyes to relieve himself of the symptom, and as the muscular lethargy begins to be felt, content to lie perfectly still as if asleep. In full doses the depressing influence involves the other branches of the nerve and the lazy movements of the eyeball, or dull fixed and occasionally divergent stare, indicate the partially paralysed...
Page 587 - Though very conspicuous, they are attended with little or no sensation, the subject being unaware of their existence until he happens to see himself. Persons have frequently been asked what was the matter, if they had measles, when they were not aware of the eruption.
Page 238 - I have not hitherto seen described, was a feeling of profound and most unusual depression, accompanied by so much irresolution and want of confidence in my own powers as to render me quite unfit for work of any kind. This invariably followed even a single five-grain dose ; and, beginning with dulness and heaviness, ran on into very much that sort of melancholia which I imagine jaundice sometimes produces.
Page 592 - As to the transient kind, we find it on many occasions a very passing phenomenon, lasting only a few seconds, then disappearing ; then, ' after a few minutes, reappearing. In this transient form, images in the median vertical line appear double, distant objects at first undergoing the duplication. Sometimes the patient was conscious of the onset of the diplopia. Thus, one woman said : 'I know it is now coming on, I feel such a heavy weight under my upper eyelid.
Page 372 - It shall be done,' said Crito, ' but consider whether you have anything else to say.' " To this question he gave no reply ; but shortly after he gave a convulsive movement, and the man covered him, and his eyes were fixed, and Crito, perceiving it, closed his mouth and eyes.
Page 439 - ... blood under the skin. October 23. His pulse continued full, and the arm was very painful, though reduced in size. The vesications had burst, and the exposed cutis was dressed with white ointment. Stools were procured by an opening medicine. He took some veal and porter for dinner ; the wine was left off. In the evening he had a saline draught with antimonial wine. October 24. There was no material change. October 25. His pulse had increased in frequency, but in other respects he was nearly the...
Page 277 - Both large and small (not very small) doses have a depressant action on the motor nerves. " 7. It paralyzes the pneumogastric nerves. " 8. Doses of moderate size diminish the excitability of the striated muscles. " 9. The local application of cocaine to any of the more highly constituted organs or tissues causes a temporary cessation of their functional activity.
Page 373 - I have often been affected with a weakness and dazzling of my eyes, together with a giddiness and debility of my whole body, especially the muscles of my legs and arms ; so that when I attempted to walk I was apt to stagger like a person who had drunk too much strong liquor.
Page 379 - ... stove. It occurs independently of any dilatation of the pupil, and is compatible with good definition for fixed objects. It is due to imperfect adjustment of the refracting media of the eye from partial paralysis of the ciliary branches of the third nerve. It is through these minute branches that the individual first becomes conscious of the effect of hemlock, and if he should be reading at the time, he will suddenly find the occupation fatiguing, and, very soon afterwards, it may be impossible...
Page 474 - He continued the same medicines, drank plentifully of whey, and was kept in a sweat, by which he found some ease at night ; but whenever the sweating lessened, the burning pains returned in broad flakes, changing from one part of the body to the other ; sometimes with shootings in the eye, and sometimes along the penis, but he had no heat of urine.

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