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99mTc bone scan 99mTc HEDP acute areas of increased arthritis biopsy bladder bone disease bone imaging bone metastases bone scan Bone scan shows bone scanning agents breast cancer calcification carcinoma cervical spine Charkes chest clinical concentration diagnosis diphosphonate Ewing's sarcoma femur focal abnormality focal area gamma camera generalised high uptake humerus hyperparathyroidism iliac increased activity increased uptake infarction injection involvement isotope joint kidney knee lateral view lesion localised long bones lumbar spine lung malignant mastectomy metabolic metastatic disease multiple myocardial normal bone scan normal radiographs Nucl nuclear medicine old woman osteoarthritis osteogenic sarcoma osteomyelitis osteosarcoma Paget's disease pain patients pelvis polyphosphate positive bone scan Posterior view primary tumour prominent prostate pyrophosphate pyrophosphate bone scan radiation radio radiograph Radiology radiopharmaceutical renal images repeat bone scan scan appearance scan demonstrates scan was obtained scapula shoulder skeletal metastases soft tissue sternum technetium therapy thoracic spine tibia tients tion trauma typical vertebrae