Beta-Blockers in Hypertension and Angina Pectoris: Different Compounds, Different Strategies

Front Cover
Springer Science & Business Media, Jun 30, 1995 - Medical - 89 pages
0 Reviews
"Knowledge desires increase - it is like fire that first must be kindled by some external agent, but which will always afterward propagate itself". Johnson, Letter to William Drummond August 13, 1776 The therapeutic effectiveness and safety of beta-adrenergic blocking drugs has been well established in patients with essential hypertension and arteriosclerotic cardiovascular disease. These drugs are useful in primary protection against cardiovascular morbidity or mortality in patients with essential hypertension and secondary protection (mor bidity and mortality in patients with myocardial infarction). Although there are mass action effects common to all of beta-adrenergic block ing agents, these agents differ in their effects on the RAS system, beta blockade, norepinephrine release, CNS effects, peripheral vas cular resistance, inotrophic effects, vasomotor effects, and effects on plasma volume. Dr. Ton J. M. Cleophas has addressed this problem of different com pounds and different strategies in the use of beta-adrenergic blockers. In Chapter 1 of this book the author deals with the problem of paradoxical pressor responses from non cardioselective beta blockade. Chapter 2 deals with a review of the literature dealing with these pressor responses which are usually thought to be mild and occur in situations of increased sympathetic activity (57 references). Chapter 3 deals with the benefi cial effects of alpha blockade in Raynaud's Syndrome, and the effect of beta blockade in counteracting the alpha blocker side effects of fluid retention and tachycardia.
 

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

INTRODUCTION AND OUTLINE OF CURRENT WORK
1
12 Outline of Current Work
2
PRESSOR RESPONSES FROM NONCARDIOSELECTIVE BETABLOCKERS
5
23 Controlled Studies Designed to Demonstrate Pressor Responses from Noncardioselective BetaBlockers
6
24 Other Studies Demonstrating Pressor Responses from Noncardioselective BetaBlockers
12
25 Conclusions
15
ALPHABLOCKER INDUCED HYPOTENSION AND FLUID RETENTION PREVENTED BY NONSELECTIVE BETABLOCKERS
21
32 Subjects and Methods
22
53 Results
48
54 Discussion
52
A PRESSOR EFFECT OF NONSELECTIVE BETABLOCKERS DURING SURGERY UNDER ANESTHESIA
59
62 Patients and Methods
60
63 Results
62
64 Discussion
66
A PRESSOR EFFECT OF NONSELECTIVE BETABLOCKERS IN UNSTABLE ANGINA PECTORIS
69
71 Introduction
70

33 Results
25
34 Discussion
29
A PRESSOR EFFECT OF NONSELECTIVE BETABLOCKERS IN DIABETICS WITH POSTURAL HYPOTENSION
34
42 Subjects and Methods
35
43 Results
38
44 Discussion
42
A PRESSOR EFFECT OF NONSELECTIVE BETABLOCKERS DURING ACUTE HOSPITALIZATION
45
52 Patients and Methods
46
73 Results
73
74 Discussion
77
MORE ON PARADOXICAL PRESSOR EFFECTS OF NONSELECTIVE BETABLOCKERS
81
82 Controlled Studies Designed to Demonstrate Pressor Responses from Nonselective BetaBlockers
82
83 Other Studies Demonstrating Pressor Responses from Nonselective BetaBlockers
85
84 Conclusions
86
Copyright

Other editions - View all

Common terms and phrases

Bibliographic information