This book is a comprehensive introduction to the expression of tumor markers in association with various neoplasms, the methods used in their detection and their clinical relevance to the diagnosis and treatment of cancer. It will be an invaluable guide for clinicians, pathologists and research workers requiring an in-depth introduction to this subject and, with sections devoted to the exploitation of new techniques in immunohistochemistry, flow cytomtry, cancer genetics and molecular biology for the identification of tumor markers, can also be used as a laboratory reference.
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a bone 2 S ?? CONTENTS Preface Introduction
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acid activity adenocarcinoma adenomas amplification analysis aneuploid anti antigen apoptosis assay associated benign binding bladder breast cancer breast carcinoma Cancer Res cell cycle cell lymphoma cell tumors cellular chain chromosome Clin clinical colon correlation counter-stain cytokeratin cytoplasm detection diagnosis differentiation DNA content Eissa endothelial enzyme epithelial estrogen expression flow cytometry follicular gene rearrangements genetic glands grade growth factor histologic Hodgkin's disease hormone human hybridization immuno immunoglobulin immunohistochemical immunohistochemistry immunoreactivity immunostaining invasive keratin laminin large cell lesions leukemia lung lymph node lymphocytes lymphoid malignant melanoma membrane metastatic method molecular molecules monoclonal antibodies mutations negative neoplasms normal nuclear oncogene Oncol ovarian over-expression P-glycoprotein paraffin-embedded Pathol patients PCNA phenotype ploidy positive primary probe prognostic proliferation proliferative protein reactivity receptor renal S-phase S-phase fraction sarcoma sequence serum small cell specific squamous cell carcinoma staining suppressor genes T-cell technique therapy tion tissue tumor cells Tumor Markers vimentin