Ocular Angiogenesis: Diseases, Mechanisms, and Therapeutics

Front Cover
Joyce Tombran-Tink, Colin J. Barnstable
Springer Science & Business Media, Nov 6, 2007 - Medical - 412 pages
Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge concerning abnormal growth of blood vessels in the eye, the cause of major neovascular eye diseases. The authors also identify and assess the most promising approaches with potential for commercial exploitation and discuss the challenges encountered in developing therapeutics for ocular neovascular diseases. Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches.
 

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Contents

C
3
OMPANION CD
5
f at the end of the file name identifies the corresponding figure in the text The CD is compatible with both Mac and PC operating systems CHAPTER ...
11
Endogenous Angiogenic Inhibitors in Diabetic Retinopathy
23
Corneal Angiogenesis
45
FIG 1
46
Polypoidal Choroidal Vasculopathy
73
Myopic Choroidal Neovascularization
85
Genetics of Ocular Vascular Disease
173
Vascular Endothelial Growth Factor and Retinal Diseases
191
The Role of Fibroblast Growth Factors
205
Control of Neovascularization and Cell Survival
215
and Tissue Inhibitors of Metalloproteinases
257
Integrins in Ocular Angiogenesis
279
Ocular Inflammation and Neovascularization
291
AntiVEGF Therapies for Diseases
309

Mechanisms of the Formation and Stability
101
FIGS 18
117
Neovascular Glaucoma
127
FIG 2
131
Eales Disease
149
Angiogenesis and Ocular Tumorigenesis
161
A Novel Ocular Angiostatic Agent
341
Gene Therapy for Neovascular Retinopathies
355
Noninvasive Delivery of DNA Into the Eye
373
Novel Drug Delivery Systems for Posterior Segment
393
Index
409
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