Connective Tissue: Macromolecular Structure and EvolutionThis book deals primarily with the principal extracellular macromole cules of animal connective tissues. It attempts to answer some general questions about the biological organization of the tissues: What is the nature of this organization at various dimensional levels? What functions does the organization serve? How has it evolved? I have given major emphasis to the structures and properties of the macromolecular components of extracellular matrices from a wide range of invertebrates and vertebrates. In doing so, however, I have treated cursorily many important aspects of connective tissue biology that appeared to be only indirectly relevant to the principal questions asked. On the other hand, I have not hesitated to search for broad biological principles outside the prevailing conceptual boundaries of animal connective tissues and the lower molecular dimensional levels. The numerous speculations presented will, I hope, stimulate the reader to further thought and investigation. Acknowledgements My previously unpublished data that have been included in this volume could not have been obtained without the generous gifts of specimens and other assistance by a number of individuals and institutions. These are Dr. G. BERENSON of Louisiana State University, Drs. W. P. BRAKER and D. ZUMWALD of the Shedd Aquarium, Dr. S. H. CHUANG of the Univer sity of Singapore, Dr. L. G. CLARK and Mr. U. M. VARELA-DIAZ of the University of Pennsylvania, the Government of Nicaragua, Dr. E. CLARK of Cape Haze Marine Laboratories, Mr. C. E. |
Contents
| 1 | |
| 7 | |
Identification | 15 |
Invertebrates | 20 |
Aggregate Forms | 25 |
c Arthropoda | 28 |
7 | 33 |
h Brachiopoda | 39 |
b Chondrichthyes | 141 |
Calcified Cartilage Bone and Teeth | 152 |
Lower Vertebrates | 158 |
e | 164 |
ii Glycans of Shell and Mantle | 177 |
iv Amphibia | 185 |
Structure of the Linkage Region | 195 |
vi Heparan Sulfate | 203 |
Other editions - View all
Connective Tissue: Macromolecular Structure and Evolution Martin B. Mathews No preview available - 1975 |
Common terms and phrases
4-sulfate 6-S periods a1 chain adult amino acid amino acid composition appears BALAZS basement membranes Biochem biological Biophys biosynthesis bone bovine calcification carbohydrate cartilage cells Chap chemical chick Chondrichthyes chondroitin sulfate colla collagen collagen fibrils collagen molecules components connective tissue contain cornea covalently cross-links cuticle D-glucuronic acid dermatan disaccharide disaccharide periods elastin embryonic enzymes ester sulfate evolution extracellular fibers fraction fucose functions galactosamine galactose glucosamine glucose glycan glycan chains glycoproteins glycosaminoglycans hagfish helical heparan sulfate heparin hexosamine homologous hyaluronate hydroxylation hydroxylysine hydroxyproline interactions invertebrates isolated keratan sulfate linkage region linked lysine macromolecules mammalian MATHEWS matrix molecular weight notochord occur organization peptide PIEZ polyanionic glycans polypeptide polypeptide chains polysaccharide preparations present proline protein proteoglycan repeating periods Sect serine shark similar skeletal keratan sulfate skin collagen species struc structure studies suggested sulfate groups sulfate proteoglycan sulfated glycans synthesis Table tion unpubl uronic acid vertebrates


