Connective Tissue: Macromolecular Structure and Evolution

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Springer Science & Business Media, Dec 6, 2012 - Science - 320 pages
This book deals primarily with the principal extracellular macromole cules of animal connective tissues. It attempts to answer some general questions about the biological organization of the tissues: What is the nature of this organization at various dimensional levels? What functions does the organization serve? How has it evolved? I have given major emphasis to the structures and properties of the macromolecular components of extracellular matrices from a wide range of invertebrates and vertebrates. In doing so, however, I have treated cursorily many important aspects of connective tissue biology that appeared to be only indirectly relevant to the principal questions asked. On the other hand, I have not hesitated to search for broad biological principles outside the prevailing conceptual boundaries of animal connective tissues and the lower molecular dimensional levels. The numerous speculations presented will, I hope, stimulate the reader to further thought and investigation. Acknowledgements My previously unpublished data that have been included in this volume could not have been obtained without the generous gifts of specimens and other assistance by a number of individuals and institutions. These are Dr. G. BERENSON of Louisiana State University, Drs. W. P. BRAKER and D. ZUMWALD of the Shedd Aquarium, Dr. S. H. CHUANG of the Univer sity of Singapore, Dr. L. G. CLARK and Mr. U. M. VARELA-DIAZ of the University of Pennsylvania, the Government of Nicaragua, Dr. E. CLARK of Cape Haze Marine Laboratories, Mr. C. E.
 

Contents

Chapter
1
The Tissues
7
Identification
15
Invertebrates
20
Aggregate Forms
25
c Arthropoda
28
7
33
h Brachiopoda
39
b Chondrichthyes
141
Calcified Cartilage Bone and Teeth
152
Lower Vertebrates
158
e
164
ii Glycans of Shell and Mantle
177
iv Amphibia
185
Structure of the Linkage Region
195
vi Heparan Sulfate
203

c Osteichthyes Bony Fish
45
a General Considerations
58
c Fossils
65
iii Secondary Chemical Structure
77
Structural Glycoproteins
86
h Other Sources
92
ii Relationship to Skeletal Keratan Sulfate
103
c Aging
264
c Osteichthyes
285
brates
293
245
307
vi Tendon
317
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