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Hormonal and Antihormonal Activities
A New Antibiotic Julimycin BII
5 other sections not shown
acetic acid acetone ACTH activity administration adrenal alcohol amino Anal androgenic anti-estrogenic antibiotic aqueous assay aziridine benzene Biochem blood body weight Bull Calcd cell characters Chem cholesterol chromatographed configuration Control Corticotropin decrease derivatives determined dioxane dosage dose effect enzyme episulfide epoxide ester estradiol estrogen ether extracted female rats foetuses Found gave GC-content gonadotropin Hiroshi hormone hydrolysis incubation inhibition injection isolated julimycin B-II male rats mammary matrix MeOH mercuric acetate metabolism methanol method mg/kg mice mixture Miyake myogenic N-ACTH nickel peroxide nitrogen NUTAX obtained OTU's oxidation peptide Pharm pituitary plasma potency Prednisolone progesterone pyridine rabbit rat liver ratio reaction recrystallized Related Compounds Rept residue ring sesame oil Shionogi Shionogi Res similar similarity matrix sodium solution Solvent system spectra spectrum steroids structure Studies subcutaneously synthesis Table Takeda temperature Testosterone propionate Tetrahedron Letters thiamine tissue treatment yield