Cocaine: Pharamacology, Physiology, and Clinical Strategies

Front Cover
CRC Press, Oct 29, 1991 - Medical - 464 pages
0 Reviews
This book brings together for the first time state-of-the-art research from both the basic sciences and the clinical fields to present an in-depth discussion of the numerous effects of cocaine. The issues discussed include metabolism and distribution of cocaine, behavioral and electrophysiological actions of cocaine, clinical aspects of cocaine associated with addiction and abuse on cardiovascular function, and exposure of infants to cocaine during gestation. The unique, multidisciplinary perspective of this book regarding on-going research on cocaine and drug abuse will be useful to researchers, clinicians, health care practitioners, and graduate students who need to stay abreast of the most current information available on this drug.
 

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

Electrophysiologic Effects of Cocaine within the Mesoaccumbens
12
CocaineInduced Hepatotoxicity
15
Metabolic Mapping of the Effects of Cocaine in the Brain
35
The Role
73
Neurobiological Mechanisms of the Reinforcing and Discriminative
91
Sensitization and Kindling Effects of Chronic Cocaine
115
Neurochemical Modulation of Monoamines by Cocaine
163
A Cocaine Receptor Associated with Dopamine Transport and Drug
191
Electrophysiological Effects of Cocaine on Serotonin Neuronal
295
In Vitro Approaches to Characterizing the Electrophysiological
309
Neuroendocrine Effects of Cocaine
341
Effects of Cocaine and other Drugs of Abuse on Immune
353
Underlying Mechanisms Responsible for Cardiovascular Disorders
371
Human Studies
391
Treatment Strategies for Cocaine Detoxification
411
Index
427

Neurochemical Mechanisms of CocaineInduced Sensitization
229

Common terms and phrases

Popular passages

Page 389 - Resnick, RB; Kestenbaum, RS; and Schwartz, LK Acute systemic effects of cocaine in man: a controlled study by intranasal and intravenous routes of administration.

Bibliographic information