Anaphylaxis and Hypersensitivity Reactions

Front Cover
Mariana C. Castells
Springer Science & Business Media, Dec 9, 2010 - Medical - 361 pages
Despite wide recognition as a serious public health problem, anaphylaxis and hypersensitivity reactions remain under-recognized and under-diagnosed. This book fills the gaps in our understanding of the identification of triggers, recognition of clinical presentations, understanding of the natural history of these reactions, and selection of treatment strategies including those focused on cellular and molecular targets. The book provides a detailed examination of disease etiology, pathogenesis, and pathophysiology and their correlation to clinical practice. Forefront knowledge of the mediators and mechanisms of anaphylaxis is covered with an emphasis on how new discoveries shape our current and emerging therapies.
 

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Contents

Definition and Criteria for the Diagnoses of Anaphylaxis
1
An Epidemiological Approach to Reducing the Risk of Fatal Anaphylaxis
13
Pathophysiology and Organ Damage in Anaphylaxis
33
Mast Cells Effector Cells of Anaphylaxis
47
Basophils in Anaphylaxis
69
Protease Mediators of Anaphylaxis
89
Aspirin and NSAID Reactions Diagnosis Pathophysiology and Management
107
IgEDependent and Independent Effector Mechanisms in Human and Murine Anaphylaxis
127
Idiopathic Anaphylaxis
223
ExerciseInduced Anaphylaxis and FoodDependent ExerciseInduced Anaphylaxis
235
Mastocytosis and Mast Cell Activation Syndromes Presenting as Anaphylaxis
245
Anaphylaxis in Mastocytosis
257
Flushing and Urticarial Syndromes Presenting as Anaphylaxis
271
Pharmacologic Management of Acute Anaphylaxis
285
Drug Desensitizations in the Management of Allergy and Anaphylaxis to Chemotherapeutic Agents and Monoclonal Antibodies
297
Rapid Desensitizations for AntibioticInduced Hypersensitivity Reactions and Anaphylaxis
313

FoodInduced Anaphylaxis
145
AntibioticInduced Anaphylaxis
171
Anaphylaxis During Radiological Procedures and in the Perioperative Setting
183
HymenopteraInduced Hypersensitivity Reactions and Anaphylaxis
209
Induction of Tolerance for FoodInduced Anaphylaxis
333
Management of Anaphylaxis Relevance of Causes and Future Trends in Treatment
345
Index
355
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