Click Reactions in Organic Synthesis

Front Cover
Srinivasan Chandrasekaran
John Wiley & Sons, Jun 22, 2016 - Science - 360 pages
This book on click reactions to focus on organic synthesis, this reference work describes the click concept and underlying mechanisms as well as the main applications in various fields. As such, the chapters cover green chemical synthesis, metal-free click reactions, synthesis of pharmaceuticals, peptides, carbohydrates, DNA, macrocycles, dendrimers, polymers, and supramolecular architectures.
By filling a gap in the market, this is the ultimate reference for synthetic chemists in academia and industry aiming for a fast and simple design and synthesis of novel compounds with useful properties.
 

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Contents

Cover
Preface
reactions
13 Base catalyzed thiolepoxy ringopening
2
Applications of Click Chemistry in Drug
15
Green Chemical Synthesis and Click
2-61
Multicomponent Reactions
2-82
Synthesis of Substituted 123Triazoles
4-2
References
4-59
Applications of the CuCatalyzed Azide
4-66
Synthesis of Diverse CarbohydrateBased
6-8
Complex Macrocycles
6-33
AzideAlkyne Click Reaction in Polymer
6-73
ThiolBased Click Chemistry
7-66
and Nucleic Acids using Huisgens 3+2 AzideAlkyne
8-75
References
8-106

Catalytic Enolate Intermediates
4-18
End User License Agreement
8-118

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About the author (2016)

Srinivasan Chandrasekaran is an Honorary Professor and SERB Distinguished Fellow at the Department of Organic Chemistry, Indian Institute of Science, Bangalore, India. He received his M.Sc. and Ph.D. from the University of Madras, India, in 1967 and 1972, respectively. He was a research associate at Harvard University (USA) with Prof. E.J. Corey, and Syntex Research (Palo Alto, USA). He has published over 250 research papers in national and international journals and served as an elected member of the Bureau of IUPAC and Member of the Executive Committee of IUPAC. He is the Chairman of the National Organic Symposium Trust (NOST), India and was the President of the Chemical Research Society of India (CRSI) from 2012 to 2014. He was the editor-in-chief of Tetrahedron Letters published by Elsevier( 2007-14) and is currently on the Board of Consulting Editors. His major research interests lie in the areas of development of new synthetic methodologies and organometallic chemistry, total synthesis of natural products, homogeneous and heterogeneous catalysis, and organic materials.

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