Hormones and Signaling

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Academic Press, Oct 25, 1999 - Science - 403 pages
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Hormones and Signaling focuses on the mechanisms of gene regulation at the cellular level. It also describes the actions of hormones in modulating gene regulation and animal development.

Key Features
* Glococorticoid and mineralcorticoid signaling
* Orphan nuclear receptors
* Nuclear receptor coactivators
* Cytokines and STAT signaling
* Coordination of cAMP signaling events through PKA anchoring
* G protein-coupled extracellular Ca2+ (Ca2+0)-sensing receptor (CaR)
* Pancreatic islet development
* Genetic analysis of androgen receptors in development and disease
* Antioprogestin regulable gene switch for induction of gene expression in vivo
* Steroid receptor knockout model

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Lessons from Gene Targeting
An Emerging Family of Metabolic Regulators
Chapter 3 Nuclear Receptor Coactivators
Chapter 4 Cytokines and STAT Signaling
Chapter 5 Coordination of cAMP Signaling Events through PKA Anchoring
Roles in Cell Signaling and Control of Diverse Cellular Functions
Chapter 7 Pancreatic Islet Development
Chapter 8 Genetic Analysis of Androgen Receptors in Development and Disease
Chapter 9 An Antiprogestin Regulable Gene Switch for Induction of Gene Expression in Vivo
Phenotypes and Responses Illustrate Interactions between Receptor Signaling Pathways in Vivo

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Page 18 - Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene. Mol. Endocrinol.

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About the author (1999)

Ferid Murad was born in Whiting, Indiana. Working concurrently on an M.D. and Ph.D. in Pharmacology, Dr. Murad graduated with both degrees from Case Western Reserve University, Cleveland, Ohio, in 1965. His many honors include the Alfred S. Maschke Award for Clinical Excellence from Case Western Reserve University in 1965. He has held several distinguished positions, including Acting Chairman in the Department of Medicine and Acting Division Chief, Division of Respiratory Medicine at Stanford University. He currently is CEO and President of Molecular Geriatrics Corporation in Lake Bluff, Illinois. Dr. Murad is married and has five children.

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