Mass Spectrometry HandbookMike S. Lee Due to its enormous sensitivity and ease of use, mass spectrometry has grown into the analytical tool of choice in most industries and areas of research. This unique reference provides an extensive library of methods used in mass spectrometry, covering applications of mass spectrometry in fields as diverse as drug discovery, environmental science, forensic science, clinical analysis, polymers, oil composition, doping, cellular research, semiconductor, ceramics, metals and alloys, and homeland security. The book provides the reader with a protocol for the technique described (including sampling methods) and explains why to use a particular method and not others. Essential for MS specialists working in industrial, environmental, and clinical fields. |
Contents
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| 23 | |
| 41 | |
Methodologies for Identifying Microorganisms and Viruses | 85 |
Industrial Perspective | 109 |
Quantitative Mass Spectrometry in Support | 171 |
Determination of Pharmacokinetic Parameters | 191 |
Methods for Screening Enantioselective Interactions | 209 |
Mass Spectrometry Techniques for Analysis of Oil | 647 |
LAMCICPMS Applied to UPb Zircon Geochronology | 675 |
Hydrocarbon Processing | 707 |
MALDIMS of Polydisperse | 725 |
Mass Spectrometry in Biofuel Research | 749 |
Mass Spectrometry in Archaeology | 765 |
Archaeometric Data from Mass Spectrometric Analysis | 797 |
Laser Ablation ICPMS in Archaeology | 829 |
HydrogenDeuterium Exchange Mass Spectrometry HDXMS | 227 |
TOFSIMS Applications to Bioimaging and Biomolecule | 243 |
Accelerator Mass Spectrometry in Pharmaceutical Development | 259 |
Screening | 273 |
Mass Spectrometry for Steroid Analysis | 297 |
Forensic Applications of Isotope Ratio Mass Spectrometry | 341 |
Analysis of Triacetone Triperoxide Explosive by Mass | 373 |
Mass Spectrometry in Solar System Exploration | 391 |
Application of GC GCTOFMS to the Characterization | 407 |
Methods of Mass Spectrometry in Homeland | 419 |
Homeland Security | 441 |
Mass Spectrometry in Homeland Security | 477 |
Measurements of Surface Contaminants and Sorbed Organics | 491 |
Determination | 509 |
TopDown Proteomic Identification of Protein Biomarkers | 559 |
Determination of Dithiocarbamate Fungicides in Food | 577 |
Disinfectant and ByProduct Analysis in Water Treatment | 593 |
Determination of Chlorinated Compounds in Dialysis Water | 631 |
Spatially Resolved MS in the Study of | 845 |
Laser AblationInductively Coupled Plasma Mass | 859 |
Mass Spectrometry in Semiconductor Research | 887 |
Analysis of Thin and Thick Films | 943 |
SIMS for Organic Film Analysis | 961 |
Contribution of Secondary Ion Mass | 1017 |
ETVICPMS for Analysis of Polymers | 1063 |
Polymers | 1079 |
Mass Spectroscopy in Polymer Research | 1107 |
Laser Mass Spectrometry Applied to the Analysis of Polymers | 1135 |
Measuring Thermodynamic Properties of Metals and Alloys | 1145 |
HighPerformance ThinLayer ChromatographyMass | 1181 |
Laser Ionization Mass Spectrometry of Inorganic Ions | 1207 |
Mass Spectrometry in the SSITKA Studies | 1229 |
Applications | 1257 |
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Common terms and phrases
acid addition agents analysis analyte application approach assay biological calculated carbon cell characterization chemical Chemistry chromatography collected column common complex composition compounds concentration containing derivatization detection determination drug effect example experiments explosives extraction field Figure flow fluid inclusions fragmentation GC-MS identification imaging inclusions increase intensity internal ionization isotope ratio Journal laser levels limited liquid mass spectrometry material matrix measured metabolites method mode molecular molecules MS/MS natural observed obtained optimization organic peak peptides performed phase plant plasma preparation present protein quantitative range Rapid reaction reference reported Research sample scan Science screening selected sensitivity separation sequence shown shows signal silico solution solvent species spectra spectrum stable standard structure studies surface Table TATP techniques temperature tion tissue trap tube urine values