Gene activity in early development
Introduction: the variable gene activity theory of cell differentiation; The onset of genome control in embryogenesis; First indices of differential embryo cell function; Quantitative aspects of protein synthesis in early embryos: the role of maternal components; Transcription in early embryos; RNA sequence complexity and structural gene transcription in early embryos; Localization of morphogenetic determinants in egg cytoplasm; Lampbrush chromosomes and the synthesis of heterogeneous nuclear and messenger RNA's during oogenesis.
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DNA Constancy and Nuclear Transplantation
Direct Evidence for the Variable Gene Activity Theory
The Onset of Genome Control in Embryogenesis
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actinomycin amphibian blastomeres blastula Britten calculated cell types Chapter chromatin complexity contains cytoplasm Davidson DNA sequence Drosophila early development early embryos egg cytoplasm embryo genome embryogenesis embryos enzyme equation fertilization fraction fragments function gastrula germ cell determinants heterogeneous nuclear RNA heterogeneous RNA histone histone synthesis Ilyanassa kinetics lampbrush chromosomes lampbrush stage lobeless localization loops maternal messenger RNA mature oocyte measured mesoderm messenger RNA microtubule protein molecules morphogenetic Nemer newly synthesized normal embryos nuclei nucleotides nurse cells observed occurs oocyte oocyte RNA oogenesis pg min-1 polar granules polar lobe poly(A poly(A)RNA polymerase polysomal pool precursor present protein synthesis protein synthesis rate quantity reaction regions renaturation ribosomal RNA ribosomal RNA synthesis RNA synthesis RNA's sea urchin sea urchin eggs sea urchin embryos showed shown in Fig single copy sequence species hybrid specific activity Strongylocentrotus structural genes studies synthesis patterns tion tissues total RNA transcribed Xenopus embryos Xenopus oocytes
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