Cellular and Molecular Neurophysiology

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Academic Press, Feb 6, 2008 - Medical - 416 pages
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This third edition is the new, thoroughly revised edition of the only current, established and authoritative text focusing on the cellular and molecular physiology of nerve cells. Previously titled Cellular and Molecular Neurobiology, the new title better reflects this focus. The book is hypothesis driven rather than just presenting the facts, and the content is firmly based on numerous experiments performed by the top experts in the field. While the book does cover the important facts, it also presents the background for how researchers arrived at this knowledge to provide a context for the field. It teaches not only how excitable cells work in detail, but also how to construct and conduct intelligent research experiments. This book promotes a real understanding of the function of nerve cells that is useful for practicing neurophysiologists and students in a graduate-level course on the topic alike.

* 80% new or updated material
* Fifteen appendices describing neurobiological techniques are interspersed in the text
* Now in full color throughout, with more than 400 carefully selected and constructed illustrations
* Provides an instructor website with all the images in electronic format, plus additional material

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About the author (2008)

Constance Hammond is an INSERM director of research at the Mediterranean Institute of Neurobiology. A renowned Parkinson's disease investigator, in 2012 she became a Chevalier of the Légion d'Honneur in recognition for her services to scientific communication. Studying biology at the University of Pierre and Marie Curie and the Ecole Normale Supérieure in Paris she completed her thesis in neurosciences at the Marey Institute in Paris, directed by Prof. D. Albe-Fessard. Guided by her curiosity and her constant desire to learn, she changed lab and research domains several times. With the knowledge of other systems and the mastering of other techniques she finally came back to her first and preferred subject of research; the role of the subthalamic nucleus in the basal ganglia system in health and Parkinson's disease.

After many years of lecturing neurobiology to biology and psychology students it became apparent that students were in need of a book to help understand the basic principles of cell electrophysiology. Discussions with Philippe Ascher convinced her that the best way to approach the subject was to explain ionic currents and potential changes in terms of single channels and unitary currents, describing pioneering neurobiological experiments. This first book "Neurobiologie Cellulaire" (written in French with her colleague Danièle Tritsch) appeared in 1990. Its immediate success inspired her to completely revise the book content and publish it in English giving it to a larger audience; Appearing in 1996 the fist edition of "Cellular and Molecular Neuroscience" was born.