Cytokine-induced Tumor Immunogenicity: From Exogenous Molecules to Gene Therapy
Academic Press, 1994 - Medical - 488 pages
This remarkable book focuses on the field of cytokines and tumor immunogenicity, in which there has been a recent resurgence of interest, especially with the advent of gene therapy. With major sections devoted to concepts, experimental models, and clinical perspectives, this volume includes chapters from nearly every research group actively contributing to this area. The excitement that pervades the field is captured, and the prospects for the future discussed. The information presented here will provide essential reading for a wide spectrum of basic as well as clinical investigators interested in cytokines and the prospects for successful cancer therapy.
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The immunogenicity of tumors
Identification of tumor rejection antigens
8 other sections not shown
Acad Sci USA activity allogeneic Anichini antibodies antigen presentation antigens recognized antitumor response autologous tumor bladder Bubenik Cancer Res carcinoma CD4+ CD8+ T cells cell lines cellular class I MHC clinical CTL clones cytokine cytokine genes cytolytic cytotoxic dose effector elicit encoding experimental expression fibrosarcoma Forni G G-CSF Gansbacher gene therapy gene transfer genetically Golumbek host human melanoma human tumor IFN-Y gene IFN-Y producing IL-2 gene immune response immune system immunogenic Immunol immunological immunotherapy induced infiltrating inhibition injected interleukin irradiated Karasuyama LAK cells leukemia lymphocytes lymphokine lysis macrophages mediated melanoma melanoma cells metastatic mice mouse murine mutated Natl Acad Sci oncogenic Parmiani G peptide Proc Natl Acad producing tumor proteins receptor recombinant regression retroviral vectors Rosenberg secreting studies syngeneic T-cell target therapeutic transduced transfected transplantation treatment tumor antigens tumor cells tumor growth tumor rejection tumor specific tumor-infiltrating tumorigenicity vaccines viral virus vitro vivo