Lung Cancer: Advances in Basic and Clinical ResearchHeine H. Hansen Primary lung tumors are now a global health problem. The incidence has risen dramatically during the last 5--6 decades, reflecting the popularity of cigarette smoking. In this, the fifth volume dealing with lung cancer in the series KappaCANCER TREATMENT AND RESEARCHkappa, many current research topics are covered by notable authorities, including chemoprevention, growth factors, multidrug resistance, new agents, and haematopoietic growth factors. Altogether, the 17 chapters from twelve countries highlight some of the rapid developments taking place in basic and clinical research of lung cancer. These chapters not only give up-to-date information, they will also stimulate further research into this man-made disease which was almost unheard of a century ago. |
Contents
Lung cancer chemoprevention | 43 |
Smoking cessation programs | 75 |
implications for early detection | 91 |
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aclarubicin activity adenocarcinoma agents antibodies assay biological bombesin bronchial cancer cell lines Cancer Res carcinogenesis carcinogens cell lines cell lung cancer chemoprevention chemotherapy chest cisplatin Clin Oncol clinical trials combination daunorubicin detection developed disease dose doxorubicin edatrexate effects epithelial etoposide evaluation expression Gazdar gene genetic GM-CSF growth factors histological human lung cancer IFNa IFNy increased induced inhibit interferon lesions lung cancer cell lung cancer patients lung carcinoma lung tumors lymph nodes malignant markers mediastinal mediastinoscopy metastases mg/m² multidrug resistance mutations Natl Cancer Inst neuroendocrine nicotine non-small cell lung NSCLC oncogene overexpression paclitaxel peptides Phase II trials Proc protein psychosocial pulmonary blastoma radiotherapy receptors recombinant response rate retinoids risk SCLC SCLC cell lines sensitivity small cell lung specific squamous cell carcinoma stage survival therapy Thorac tissue tobacco topoisomerase topoisomerase II toxicity treatment tumor cells verapamil vitamin vitro xenografts