Nutraceuticals in Health and Disease Prevention
Klaus Kramer, Peter-Paul Hoppe, Lester Packer
CRC Press, May 15, 2001 - Medical - 318 pages
Promoting scientific support for the plethora of health benefits related to nutrition and medicine, Nutraceuticals in Health and Disease Prevention delivers a comprehensive and scientifically sound overview of the latest research findings in disease prevention, therapy, and enhanced body function in the revolutionary field of nutraceutical technology-with highlights from the Nutraceutical Conference held in Ludwigshafen, Germany.
Includes perspectives and reviews from recognized experts on nutraceuticals of scientific and public interest!
Recognizing the need to control the balance between environmental stressors and human health, Nutraceuticals in Health and Disease Prevention
Containing over 1100 valuable literature references, drawings, and tables, Nutraceuticals in Health and Disease Prevention functions as an indispensable reference in the libraries of nutritionists and dietitians, pharmacists, molecular and cell biologists and biochemists, oncologists, endocrinologists, dermatologists, physiologists, epidemiologists, neurochemists, pediatricians, and upper-level undergraduate, graduate, and medical school students in these disciplines.
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Nutraceuticals The Link Between Nutrition and Medicine
The Role of Vitamin E in the Emerging Field of Nutraceuticals
SAdenosylmethionine SAMe Preclinical and Clinical Studies in Depression
SAdenosylLMethionine The Healthy Joint Product
Methyltetrahydrofolate The Superior Alternative to Folic Acid
Lycopene and Lutein The Next Steps to the Mixed Carotenoids
n3 Polyunsaturated Fatty Acids from Fish Effects on Coronary Artery Disease
Lipoic Acid A Multifunctional Nutraceutical
Creatine Physiology and Exercise Performance
Plant Phenols and Cardiovascular Disease Antioxidants and Modulators of Cell Response
LCarnitine and Its Precursor 𝛾Butyrobetaine
Conjugated Linoleic Acid
Contributions of Different Types of Evidence
The Brave New World of Foods That Make HealthRelated Claims
Other editions - View all
3-carotene 5-methyltetrahydrofolate activity animals antioxidant ascorbate atherosclerosis bioavailability Biochem Biophys Biol biological biosynthesis blood cancer carnitine carnitine deficiency carotenoids cellular Chem CLA intake Clin Nutr clinical compounds concentration Conjugated linoleic acid coronary creatine supplementation decreased diabetes diet dietary supplement dihydrolipoic acid dose drug effect endothelial cells enzyme factor fatty acids FDC Act flavonoids folate folic acid free radicals function gene glucose glutathione health claim homocysteine human increased induced inhibition insulin isomers L-carnitine L(-)-carnitine labeling levels lipid lipoic acid lipoprotein liver lutein lycopene membrane metabolism methionine methyl mitochondrial molecules n-3 PUFA neuropathy NF-kB nutraceuticals nutrient nutritional o-lipoic acid oral oxidative stress Packer pathway patients Pharmacol phenolic placebo plasma prevention protein R-lipoic rats reduced reductase regulation risk role S-adenosylmethionine serum skeletal muscle skin studies synthesis tion tissue treatment Tritschler tumor uptake vitamin B12 vitro vivo Y-butyrobetaine
Page v - Free radicals can be overproduced or the natural antioxidant system defenses weakened, first resulting in oxidative stress, and then leading to oxidative injury and disease. Examples of this process include heart disease and cancer. Oxidation of human low-density lipoproteins is considered the first step in the progression and eventual development of atherosclerosis, leading to cardiovascular disease. Oxidative DNA damage initiates carcinogenesis. Compelling support for the involvement of free radicals...
Page v - More and more evidence is accumulating that a proper balance between oxidants and antioxidants is involved in maintaining health and longevity, and that altering this balance in favor of oxidants may result in pathological responses causing functional disorders and disease.
Page iv - ... necrosis). Virtually all diseases thus far examined involve free radicals. In most cases, free radicals are secondary to the disease process, but in some instances free radicals are causal. Thus, there is a delicate balance between oxidants and antioxidants in health and disease. Their proper balance is essential for ensuring healthy aging. The term oxidative stress indicates that the antioxidant status of cells and tissues is altered by exposure to oxidants. The redox status is thus dependent...
Page iv - S) do not spontaneously form because sulfhydryl groups kept in the reduced state (SH) prevent protein misfolding or aggregation. This reducing environment is maintained by oxidative metabolism and by the action of antioxidant enzymes and substances, such as glutathione, thioredoxin, vitamins E and C, and enzymes such as superoxide dismutase (SOD), catalase, and the selenium-dependent glutathione and thioredoxin hydroperoxidases, which serve to remove reaction oxygen species.