Handbook of Carcinogen TestingHarry A. Milman, Elizabeth K. Weisburger |
Contents
Role of Epidemiology in Identifying Chemical Carcinogens | 28 |
Studies of Occupational Carcinogenesis | 37 |
Other Exposures Waste Disposal Accidents Ambient | 44 |
Copyright | |
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acid activity addition administration agents animals appear asbestos assay assessment associated bioassay biological Cancer Res carcinogenesis carcinogens carcinomas cause cells changes chemical chrysotile communication compared compounds concentration considered containing culture cytoplasm demonstrated detected determine diet dose effects Environ estimate evaluation evidence examined example experimental experiments exposed exposure factors fibers Figure foci given hamsters Health human important incidence increased induced initiation interpretation known laboratory lesions levels limited liver lung male mammary metabolic methods mice mineral months mouse mutagenicity natural neoplasms normal observed occur organs period peroxisome positive possible potential present procedures produced proliferation promotion rats reference reported Research response risk sensitive shown significant skin species spontaneous standard statistical strains studies substances Table tion tissue toxicity Toxicol transformation tumor promoters various vitro weeks