Many noteworthy advances in our knowledge of the pericardium, its functions and diseases and their relation to heart failure have been made since the first edition of this book appeared in 1981; and no other book that covers in detail the physiology and pathophysiology has since been published. The first edition was favourably received, and I have frequently been asked to write a new edition. My own knowledge in the years that have passed since then, and my clinical and research experience in the field of the subject have both increased. For all these reasons, I decided that the second edition was overdue. The long time that has elapsed between editions necessitated rewriting, rather than simply revising, most of the text. For the same reason, many of the figures are new. Most of the references I have cited appeared in the literature after 1981, but I have retained a number of earlier ones, either because they are classics or, in my opinion, have not yet been bettered. It is my hope that the new edition will be a useful resource for clinicians called upon to manage patients with pericardial disease and for physiologists when the pericardium is relevant to their investigations. I make no apology for the in-depth treatment of the pericardial physiology and pathophysiology throughout the book, for they are the foundation on which diagnosis, hemodynamic and imaging studies, and management must rest.
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PERICARDIOCENTESIS Pericardioscopy and pericardiotomy
CONSTRICTIVE PERICARDITIS Hemodynamic comparisons with tamponade and restrictive cardiomyopathy
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abnormal acute pericarditis aetiology aortic atrium biopsy blood canine cardiac output cardiac tamponade Cardiovasc catheter cause chest chronic chylopericardium Circulation clinical Coll Cardiol collagen compression constrictive pericarditis coronary curve diagnosis dogs Doppler dysfunction early diastolic echocardiography effect electrocardiogram elevated epicardial Figure flow Fowler function heart failure hemodynamic imaging infection inspiration intrapericardial left atrial left heart left ventricle left ventricular diastolic lymphatic measured mechanism mediastinal mitral mmHg myocardial infarction myocardium needle normal pathophysiology patients percent pericardial disease pericardial effusion pericardial fluid pericardial pressure pericardial space pericardiectomy pericardiocentesis permission Physiol pleural pressure-volume pulmonary arterial pulmonary venous pulsus paradoxus respiration respiratory variation restrictive cardiomyopathy right atrial pressure right heart right ventricle right ventricular diastolic septum severe Shabetai Spodick stroke volume syndrome systemic venous return systolic thoracic transmural pressure treatment tricuspid tuberculosis valve velocity vena cava venous pressure ventricular diastolic collapse ventricular diastolic pressure ventricular filling ventricular interaction ventricular pressure ventricular volume