Chemistry and Pharmacology
Academic Press, Aug 31, 1995 - Science - 364 pages
Internationally acclaimed for more than forty years, this serial, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structureelucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, or various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Over the years, this series has become the standard in natural product chemistry to which all other book series aspire. The Alkaloids: Chemistry and Pharmacology endures as an essential reference for all natural product chemists and biologists who have an interest in alkaloids, their diversity, and their unique biological profile.
* Indispensible reference work written by leading experts in the field
* Provides up-to-date, timely reviews on compounds and classes of great interest
* Covers synthesis, biosynthesis, biology, as well as isolation and structure elucidation
* An essential research tool for anyone working with alkaloids from a chemical or biological perspective
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Chapter 2 Pharmacology of Polyamine Toxins from Spiders and Wasps
Chapter 3 Epibatidine
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a-N-metho salt abbreviatus absolute conﬁguration acid amino analogs ancistrobrevine Ancistrocladaceae ancistrocladine atropisomer benzophenanthridines berberine biaryl biogenetic Biological activity biosynthetic Bringmann cadaverine CHCl chelerythrine chelidonine Chem chiral compounds conﬁrmed Corydalis corynoline 12 coupling COZH D. J. Robins degradation derivative dihydrochloride dihydrosanguinarine dimeric Dioncophyllaceae dioncophylline efﬁcient enantiomer enzyme epibatidine feeding experiments ﬁndings ﬁrst glutamate heyneanus homospermidine hydroxylation incisa incorporation intermediate isolated isomer isoquinoline korupensamine korupensis lupinine methanol methyl michellamines molecules N-metho N-methyl naphthalene naphthylisoquinoline alkaloids natural product necines NMDA receptors obtained OCHZO OMe OMe OMe ophiocarpa oxidation oxygen function pathway peltatum Perkin Trans Phytochemistry plants polyamine toxins potent precursor produce protoberberines protopine puriﬁed putrescine pyridine quinolizidine quinolizidine alkaloids racemic reaction relative conﬁguration retronecine retrorsine ring sanguinarine Scheme scoulerine Section Senecio sparteine species speciﬁc Spectroscopy spider stereocenters stereochemical stereochemistry stereoselective Structure Elucidation stylopine substituent substrate synthetic Table tetrahydroprotoberberines total synthesis triphyophylline unpublished results venom