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The Plasma Lipoproteins
Lipoprotein Biosynthesis and Metabolism By RICHARD J HAVEL
The Origin of LowDensity and High
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A-II activity addition amino acid amount apoA-I apoB apoC-II apoE apolipoproteins appears associated bilayer binding Biochem Biol Biophys cells changes Chem cholesterol cholesteryl esters chromatography complex components composition concentration conformation containing core decrease degradation density described determined DISCUSSION distribution DMPC effect electron evidence experiments FIGURE fluorescence fraction function GOTTO helical helix human hydrophobic important increase incubation indicated injected interaction interface involved isolated label LCAT lipid lipoprotein lipoprotein lipase liver mean measured membrane method mixture molecular molecules monolayer normal observed obtained occurs particles peptide phospholipid plasma polarization possible predicted prepared present pressure properties protein question ratio receptor region relatively removed residues scattering sequence serum shown similar solution specific structure studies suggest surface TABLE techniques temperature tion tissues transfer transition ultracentrifugation uptake vesicles vivo VLDL weight York