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active sleep agonists airway animals Appl Physiol arousal associated atonia autonomic behavioral benzodiazepine Biol blood Brain Res brainstem cells cent cerebral changes cholinergic chronic circadian rhythms Clin Neurophysiol clinical cortex cortical cycle daytime sleepiness decrease Dement WC desynchronized doses dream drugs Electroencephalogr Clin electroencephalogram entrainment episodes forebrain function hamster humans hypnotics hypothalamus increased inhibition inhibitory insomnia latency lesions mechanisms membrane metabolic motoneurons motor muscle narcolepsy neurons Neurosci night nocturnal normal NREM nucleus obstructive sleep apnea occur oscillator patients pattern PGO waves phase phasic physiological pontine potential Psychiatry rapid eye movements receptors regulation REM sleep reported Respir response reticular formation sleep and wakefulness sleep deprivation sleep disorders sleep loss sleep onset Sleep Res sleep stages sleep-related sleep-wake slow wave activity slow wave sleep snoring specific spike spindle stimulation studies subjects suprachiasmatic suprachiasmatic nucleus synaptic thalamic tion total sleep York