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Cerebral cortex pathology in aging and Alzheimers disease
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activity ADAS-Cog allele Alzheimer disease Alzheimer's disease amyloid analysis anti-inflammatory APOE APOE4 apolipoprotein apoptosis assessment associated astrocytes baseline behavioral brain regions caregivers cells cerebral cholinergic cholinesterase cholinesterase inhibitors clinical trials cognitive decline cognitive function cognitive impairment correlated cortex cortical decreased deficit demented depression diagnosis disorders donepezil dose drugs dysfunction effects elderly evaluation extrapyramidal signs fall-related genes genetic Geriatr glutamate hippocampus increased inflammatory inhibitors injury lesions levels Lewy body memory metabolism metrifonate microglia MMSE mutations neocortical neurodegenerative neurofibrillary neurofibrillary tangles neuroleptic Neurology neurons neuropathological neuropsychological Neurosci neurotransmitter NMDA normal NRHypo nursing home nutritional olfactory onset pathological physical restraint placebo plaques predictors progression propentofylline protein psychiatric rats receptors reduced reported restraint reduction risk factors SAMP8 score senile significant significantly specific stage studies subjects survival symptoms syndrome tau protein therapy treatment type 2 diabetes vascular dementia vitamin