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THE CHROMOSOMAL BASIS OF HEREDITY
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abortions affected children alleles amino acid antibody antigens autosomal dominant autosomal recessive biochemical birth blood group blood group system carrier centromere chain Chapter child chromatin chromo chromosome abnormalities chromosome number clinical common congenital culture defect deficiency deletion dermatoglyphics determined disease DZ twins enzyme example expressed females fetal fetus frequency G6PD gametes gene genetic disorders genotype hemoglobin heterozygotes heterozygous homozygotes homozygous human hybrid inactivation individual inheritance karyotype known linkage loci locus males malformations maternal mating meiosis meiotic division metabolism molecule mother mouse multifactorial mutation rate nondisjunction normal offspring pair parents patients patterns pedigree percent phenotype polymorphism polypeptide population probability produce protein rare recombination red cells relative retardation risk sequence serum sibs sibships sickle cell single somatic cell specific structure studies syndrome synthesis thalassemia tion tissue trait translocation trisomy Turner syndrome types usually variants X chromosome X-linked