Frontiers in Celiac Disease

Front Cover
Alessio Fasano, Riccardo Troncone, D. Branski
Karger Medical and Scientific Publishers, Jan 1, 2008 - Medical - 222 pages
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Few other fields in human biology have experienced such a tremendous progress as celiac disease has during the past few years. The contributors to 'Frontiers in Celiac Disease' are world-renowned opinion leaders who made these advances possible. Their expertise has been assembled here to provide a comprehensive overview of the current knowledge of the epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of celiac disease. In addition, the stage is set for innovative strategies for preventive interventions and treatment alternatives to a gluten-free diet. A valuable reference for basic and translational scientists, this book also serves as a practical resource to healthcare professionals, including general practitioners, subspecialists, dieticians, nutritionists, and nurses and nurse practitioners. Students from different disciplines will find this book a helpful guide to expand and deepen their knowledge of celiac disease.
 

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Contents

Natural History of Celiac Disease
12
The Changing Clinical Presentation of Celiac Disease
18
HLA and NonHLA Genes in Celiac Disease
32
Twins and Family Contribution to Genetics of Celiac Disease
46
Biochemistry and Biological Properties of Gliadin Peptides
57
Innate Immunity and Celiac Disease
66
Across the Threshold of Tolerance
82
The Role of the Intestinal Barrier Function in the Pathogenesis of Celiac Disease
89
Current Guidelines for the Diagnosis and Treatment of Celiac Disease
107
Current Therapy
114
The National Institutes of Health Consensus Conference Report
133
Oral Glutenase Therapy for Celiac Sprue
148
Development of a Vaccine for Celiac Disease
172
Strategies for Prevention of Celiac Disease
188
Animal Models of Celiac Disease
210
Copyright

Diagnosis of Coeliac Disease Open Questions
99

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About the author (2008)

Director, Center for Celiac Research, Massachusetts General Hospital

Bibliographic information