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1Dept amino acid analysis antibodies assay Bethesda binding Biochemistry Cancer Research cDNA cell lines cellular Center characterized cleavage clones complex conserved containing cytoplasmic deletion Dept detected dimerization domain ecotropic elements encoded endogenous enhancer Env protein envelope proteins factors function fusion gene expression genetic genome glycoprotein HTLV HTLV-I immunodeficiency virus Immunology induced infected cells inhibition Institutes of Health integrase integration interaction isolated Laboratory of Molecular M-MuLV macrophages Maryland Medical mice Microbiology Molecular Biology Moloney mRNA MuLV murine leukemia virus mutant National Institutes nef gene NF-kB nucleotide particles phenotype plasmid polymerase processing protease proviral proviruses receptor recombinant region replication residues retroviral retroviruses reverse transcriptase RNase H role School of Medicine sequences specific splicing structure studies suggest syncytium T-cell target Tat protein transactivation transfected tumors University V3 loop vector viral DNA virions Virology viruses vitro vivo wild type wild-type