Diabetes and Hypertension
F.A. Gries, P. Weidmann
Springer Berlin Heidelberg, Aug 19, 1988 - Medical - 137 pages
The association of diabetes mellitus and hypertension has been well known for a long time. However, the important impact of hypertension on the development of chronic complications of diabetes and on the prognosis of the diabetic patient has only recently been realized. The increasing number of patients with endstage diabetic nephropathy who need regular dialysis or renal transplantation reflects only one important aspect of this problem. As new targets for the treatment of hypertension were considered, it became evident, that drug treatment of hypertension in diabetics must take side effects into account which may be negligible in the nondiabetic patient. Basic research has granted much new insight into the mechanisms which function to link diabetes, kidney function, hypertension, and vascular disease. As a result of the high specialisation in research, such new information diffuses only slowly out of the circles of experts into clinical practice. Therefore, it was a most rewarding initiative of the Bayer Company to sponsor a conference which aimed at a mutual exchange of ideas between clinicians and researchers who are experts in either hypertension or diabetes.
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Epidemiology of Hypertension and Diabetes Mellitus
Antihypertensive Therapy and Risk of Diabetes
Renal Histology in Hypertensive Diabetics
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ACE inhibitors acid alpha-ANP antihypertensive antihypertensive drugs antihypertensive treatment arteriolosclerosis artery associated Berlin Heidelberg 1988 beta-blockers blood glucose calcium calcium antagonists capillary captopril cardiac cardiovascular cells changes clinical converting enzyme inhibitors coronary correlation decreased dependent diabetics developed diabetes Diabetes and Hypertension diabetes mellitus diabetic nephropathy diabetic patients diabetic rats diabetic subjects Diabetologia dialysis diastolic diastolic blood pressure diet dietary disease DITSCHERLEIN diuretics doses eicosanoid elevated enzyme inhibitors excretion F. A. GRIES glomerulosclerosis glucose tolerance GOH conditions heart hyperinsulinaemia hypertension in diabetics hypertrophy hypoglycaemia increased insulin resistance insulin response insulin-dependent diabetics J. H. FULLER JANKA KAZDA kidney lipid mmHg myocardial nifedipine nitrendipine non-diabetics normal obesity patients with diabetic PGE2 PGI2 plasma ANP platelet population prevalence prostacyclin proteinuria reduced renal failure renal function retinopathy risk factor risk of developing RITZ sodium Springer-Verlag Berlin Heidelberg systolic blood pressure triglycerides Type II diabetics vascular vessel Weidmann Eds