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" ONYX-015. an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents. Nat Med 1997; 3: 639-645. "
Apoptosis Genes - Page 300
edited by - 1998 - 310 pages
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Molecular Biology of the Lung: Asthama and Cancer

Robert A. Stockley - Medical - 1998 - 220 pages
...Science 274: 373-376 41 Heise C, Sampson-Johannes A, Williams A et al. (1997) ONYX-015, an E1B attenuated adenovirus, causes tumor-specific cytolysis and antitumoral...standard chemotherapeutic agents. Nature Med 3: 639-645 42 Takahashi T, Takahashi T, Suzuki H et al. ( 1991 ) The p53 gene is very frequently mutated in small-cell...
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Normal and Malignant Liver Cell Growth

W.E. Fleig - Medical - 1998 - 268 pages
...1996;274:373-5. 51. Heise C, Sampson- Jonannes A, Williams A, McCormick F, von Hoff DD, Kim DH. ONYX-015, an E15 gene-attenuated adenovirus, causes tumor-specific...augmented by standard chemotherapeutic agents. Nature Med. 1997;3:639- 45. 52. Lowe SW. Progress of the smart bomb cancer virus. Nature Med. 1997;3:606-8. 53....
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Childhood Leukemias

Ching-Hon Pui - Medical - 1999 - 606 pages
...vector. Nat Med 1997:3:1 145-9. 16. Heise C, Sampson-Johannes A, Williams A. et al. ONYX015, and EI8 gene-attenuated adenovirus causes tumor-specific cytolysis...be augmented by standard chemotherapeutic agents. Nat Med 1997:3:639-45. 17. Weitzman MD, Kyostio SRM, Kotin RM. et al. Adeno-associated virus (AAV)...
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Molecular Biology of the Lung: Asthama and Cancer

Robert A. Stockley - Medical - 1998 - 220 pages
...Science 274: 373-376 41 Heise C, Sampson-Johannes A, Williams A et al. (1997) ONYX-015, an E1B attenuated adenovirus, causes tumor-specific cytolysis and antitumoral...augmented by standard chemotherapeutic agents. Nature Med3: 639-645 42 Takahashi T, Takahashi T, Suzuki H et al. (1991 ) The p53 gene is very frequently...
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The Development of Human Gene Therapy

Theodore Friedmann - Adenoviruses - 1999 - 748 pages
...C.. Sampson-Johannes A., Williams A., McCormick F., Von Hoff DD, and Kim DH 1997. ONYX-015. an EIB gene-attenuated adenovirus, causes tumor-specific...can be augmented by standard chemotherapeutic agents (see comments). Nat. Med. 3: 639-645. Hirschowitz EA. Ohwada A.. Pascal WR. Russi TJ, and Crystal RG...
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Eurocancer 2000

Michel Boiron, Michel Marty - Oncology - 2000 - 442 pages
...cells. Science 1996 ; 274 : 373-6. Heise C, Sampson JA, Williams A, McCormick F, Von Hoff D, Kirn DH. ONYX-015, an E1B gene-attenuated adenovirus, causes...augmented by standard chemotherapeutic agents. Nature Med 1997 ; 3 : 639-45. Oncolytic virus therapy of tumors EA CHIOCCA Molecular N euro-Oncology Laboratory,...
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Gene Therapy of Cancer: Methods and Protocols

Wolfgang Walther, Ulrike Stein - Medical - 2008 - 633 pages
...p53-deficient human tumor cells. Science 274, 373-376. 3. Heise, C., et al. (1997) ONYX-015, an ElB gene-attenuated adenovirus, causes tumor-specific...can be augmented by standard chemotherapeutic agents [see comments]. Nat. Med. 3, 639-645. 4. Boyle, JO, et al. (1993) The incidence of p53 mutations increases...
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Surgical Research

Wiley W. Souba, Douglas W. Wilmore - Health & Fitness - 2001 - 1526 pages
...9470-9478. 150. Heise. C.. Sampson-Johannes, A., Williams. A., McCormick, F. Von Hoff, DD, and Kirn, DH (1997). ONYX-015, an E1B gene-attenuated adenovirus,...standard chemotherapeutic agents. Nature Med. 3, 639-645. 151. Kim, D., Mermiston, T, and McCormick. F. ( 1998). Onyx-015: Clinical data are encouraging [letter...
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Viruses, Cell Transformation, and Cancer

Roger J. A. Grand - Medical - 2001 - 540 pages
...Ther 8, 1-14. Heise, C., Sampson-Johannes, A., Williams, A., McCormick, F., Von Hoff, DD and Kim, DH (1997). ONYX-015, an E1B gene-attenuated adenovirus....can be augmented by standard chemotherapeutic agents [see comments]. Nat Med 3, 639-45. Hirschowitz, EA, Leonard, S., Song, W., Ferris, B., Leopold, PL,...
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Tumor Suppressing Viruses, Genes, and Drugs: Innovative Cancer Therapy ...

Hiroshi Maruta - Medical - 2001 - 425 pages
...Clin. Invest. 105,847-851. Heise, C, Sampson, JA, Williams, A., McCormick, F, Von, HD, and Kim, DH (1997). ONYX-015, an E1B gene-attenuated adenovirus,...can be augmented by standard chemotherapeutic agents [see comments]. Nat. Med. 3,639-645. Heise, C., Williams, A., Xue, S., Propst, M., and Kirn, D. (1999)....
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