The Liver in Biology and Disease: Liver Biology in Disease, Hepato - Biology in Disease

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Elsevier, Dec 31, 2004 - Science - 600 pages
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The Liver in Biology and Disease was conceived as a sequel in the series Principles of Medical Biology, whose general aim continues to be the integration of human biology and molecular cell biology into modern molecular medicine. It is a volume molded by the Information Revolution which few will deny has forced the teaching faculties in our medical schools to curtail and prune the teaching load and focus on fundamentals and principles. With this intention in mind, a volume of this nature takes into account the close dependence of progress in the medical sciences on bioinformatics (gene and protein analysis) or more precisely, computational biology and of course, the Internet. In general, it follows the pattern of its predecessors.

*Chapters are illustrated with numerous figures and references are current
*Clear, concise and accurate text about a large number of liver diseases
*Describes the liver's histology, biochemistry, and pathology in molecular terms
 

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Contents

1 THE INTRAHEPATIC BILIARY TREE
1
2 FUNCTIONAL HETEROGENEITY OF INTRAHEPATIC CHOLANGIOCYTES
21
3 THE ACTIN CYTOSKELETON IN LIVER FUNCTION
49
4 MECHANISMS OF BILE FORMATION AND CHOLESTASIS
81
5 THE ROLE OF BILE ACIDS IN THE MODULATION OF APOPTOSIS
119
6 GROWTH FACTORS AND THE LIVER
147
7 CHEMOKINE AND CYTOKINE REGULATION OF LIVER INJURY
167
8 DRUG METABOLISM AND HEPATOTOXICITY
207
14 PRIMARY BILIARY CIRRHOSIS
383
15 CHRONIC ACTIVE HEPATITIS
399
16 HEPATITIS B VIRUS
427
17 CURRENT ISSUES IN HEPATITIS B VACCINES
439
18 THE MOLECULAR VIROLOGY OF HEPATITIS C VIRUS
455
19 THE ROLE OF THE HEPATIC STELLATE CELL IN LIVER FIBROSIS
497
20 ORTHOTOPIC LIVER TRANSPLANTATION
525
21 BIOLOGICAL PRINCIPLES AND NOVEL THERAPIES IN LIVER CELL TRANSPLANTATION
543

9 ASSEMBLY AND SECRETION OF HEPATIC VERYLOWDENSITY LIPOPROTEIN
229
10 BILIRUBIN METABOLISM
257
11 CLINICAL BIOCHEMISTRY OF THE LIVER
291
12 ALCOHOLIC LIVER DISEASE
317
13 FULMINANT HEPATIC FAILURE
361
22 FLUID TRANSPORT IN THE GALLBLADDER
555
AUTHOR INDEX
577
SUBJECT INDEX
595
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