Anthony Henry Vernon Schapira, Robert C. Griggs
Butterworth-Heinemann, 1999 - Medical - 408 pages
This concise disorder-specific clinical text on muscle diseases covers current and new concepts in patient management. Due to advances in molecular genetics, the field of muscle diseases is evolving rapidly and clinicians need to stay abreast of the latest developments in diagnosis and treatment. Neuromuscular specialists and general neurologists will benefit from the cutting edge knowledge contained within this authoritative text.
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Clinical Evaluation of Patients with Neuromuscular Disease
Muscle Pain and Fatigue
Overview of Clinical
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abnormalities Acad Sci acetylcholine receptor AChR acid activity Ann Neurol antibodies associated atrophy autoimmune Biochem calcium cardiac carnitine cause cell chloride channel chromosome chronic fatigue syndrome Clin clinical features complex congenital defects deficiency dehydrogenase deletion dermatomyositis diagnosis distal dose Duchenne effects encoded enzyme exercise fibromyalgia FSHD function gene Hum Genet Hum Mol Genet human hyperkalemic periodic paralysis hypokalemic inclusion body myositis increased infection inflammatory myopathy involvement kinase malignant hyperthermia membrane metabolism mitochondrial DNA mitochondrial myopathy molecular mtDNA muscle biopsy muscle fibers Muscle Nerve muscle pain muscle weakness muscular dystrophy myalgia myasthenia gravis myasthenic syndrome myoglobinuria myotonia congenita myotonic dystrophy Nat Genet Neurology Neuromuscul Disord neuromuscular neuropathy normal onset OXPHOS paramyotonia congenita pathogenesis patients Pediatr phenotype point mutation polymyositis potassium prednisone protein proximal reported respiratory sarcoglycan serum CK skeletal muscle sodium channel steroid studies subunit symptoms therapy tissue treatment tRNA usually