The Antibiotic Paradox: How Miracle Drugs are Destroying the Miracle
The discovery of antibiotics heralded medicine's triumph over previously fatal diseases that once destroyed entire civilizations - thus earning their reputation as miracle drugs. But today, the terrifying reality of antibiotic-resistant bacteria resulting from our widespread misuse of antibiotics forewarns us that the miracle may be coming to an end. The seemingly innocent consumer who demands antibiotics to treat nonbacterial diseases such as the common cold or plays doctor by saving old prescriptions for later use is paving the way for a future of antibiotic failure. "What harm can it do?" is a popular refrain of people worldwide as they pop another antibiotic pill. Dr. Stuart Levy - the leading international expert on hazards of antibiotic misuse - reveals how this cavalier and naive attitude about the power of antibiotics can have deadly consequences. He explains that we are presently witnessing a massive evolutionary change in bacteria. This build-up of new antibiotic-resistant bacteria in individuals and the environment worldwide is an insidious and silent process. Thus, unwittingly consumers encounter resistant bacteria in their meat, poultry, fish, and vegetables. Unregulated dispensing of antibiotics in poorer countries breeds countless more resistant strains. Since bacteria recognize no geographical boundaries, resistant forms can travel the globe. If this trend continues to grow unchecked, we may someday find that all of our antibiotics are obsolete. Today doctors can no longer expect that their first choice of antibiotic for women's urinary tract infections or children's ear infections will work. Similarly, cancer therapy is rendered useless if patients are unable to fightinfections that are sometimes resistant to eight to ten different drugs. In developing countries, people are now dying of previously treatable diseases that are no longer responsive to traditional antibiotics. These problems are just a harbinger of what will come if we do not act now. Dr. Levy, recognized by The New Yorker for his superb contributions to this field, is sending out an urgent message that the world cannot afford to ignore any longer. The goal of this unprecedented investigation into the dangers of antibiotic misuse is to protect the world community from resistant infections and ensure the success of antibiotics for generations to come.
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The Antibiotic Paradox: How Miracle Drugs Are Destroying the Miracle
Stuart B. Levy
Limited preview - 2013
amounts of antibiotics ampicillin animals anti antibacterial antibiotic misuse antibiotic resistance antibiotic usage antimicrobials appeared areas bacterial infections bacterium biotics body Bonnie Marshall cephalosporins chloramphenicol chromosome clinical coli countries cure developed diarrhea different antibiotics discovered discovery disease-causing drugs emergence environment enzymes erythromycin Escherichia coli fever Figure fish Gram-negative growth promotion hospital host human infectious agents infectious diseases intestinal tract kill kinds of bacteria Medicine microbial microorganisms multidrug resistance multiply multiresistant mutants needed numbers occur oxytetracycline pathogenic patients penicillin pharmacy physician plasmids potential prescription present produced protein quinolone resis resistance determinants resistance genes resistance mechanisms resistance problem resistant bacteria resistant forms resistant strains Salmonella scientists selection of resistant Shigella side effects skin soil spread Staphylococcus streptomycin substances sulfonamides survive susceptible tance tetracycline therapeutic therapy tion toxic traits transferable transposons treat treatment trimethoprim Tufts University Tufts University School United urinary tract infections worldwide