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6-mercaptopurine Actinomycin Action Dilution Storage acute adriamycin albumin alkylating agents Alopecia anti-cancer drugs anti-tumour activity antibiotics antimetabolite Ara-C asparaginase Bleomycin bone marrow Bone marrow depression breast cancer cancer cells cancer chemotherapy carcinoma cause cell cycle central compartment Check FBC chemo chemotherapeutic agents chlorambucil Cis-platinum Classification Action Dilution clinical trials compounds concentration cyclophosphamide cytosine cytotoxic drugs daunorubicin disease Dosage dose drug treatment enzyme excreted factors Figure fluid fluorouracil folinic acid function gastrointestinal growth fraction half-life hexamethylmelamine hormone immune response immunotherapy increased inhibitors inhibits injection interactions intrathecal kinetic leukaemia liver lymphocytes Lymphoma malignant mechanism of action melphalan membrane metabolism metabolites methotrexate mg vials mg/m Mithramycin molecule monophosphate Mucositis Nausea and vomiting normal tissues nucleic acid nucleoside oral Pharmacology phase plasma Procarbazine protein purine pyrimidine radiotherapy receptors Reconstituted reductase renal ribonucleotide serum side-effects specific stem cells steroid synthesis therapeutic therapy thymidine toxic effects tumour tumour cells urine vinblastine Vincristine