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accumulation acetylcholinesterase acrylamide actin activity amino acids ATPase axolemma axonal transport axoplasmic transport axotomy Biochem block Brain Res calcium calmodulin Cell Biol cell body cholinergic colchicine components crush cytoplasm cytoskeletal decrease desheathed diabetes distal dorsal root ganglion effect enzymes experimental fast axonal transport fast axoplasmic transport fast-transported proteins fraction fucose function giant axon glycoproteins goldfish optic increase inhibition injection intracellular labeled proteins Lasek ligation mammalian nerve mechanism metabolism microtubules mm/day molecular weight molecules motor movement muscle myelinated nerve fibers nerve terminals neurites Neurobiol Neurochem neurofilaments neurons neuropathy Neurosci observed Ochs optic nerve organelles peripheral nerve Physiol plasma membrane polypeptides proteoglycans proximal radioactivity rapidly transported rat sciatic nerve regenerating retrograde axonal transport retrograde transport role sciatic nerve sensory slow-transport soluble squid giant axon streptozotocin studies substances sulfate synthesis tissue transport of proteins transported glycoproteins transported proteins tRNA trophic tubulin velocity vitro