AXOPLASMIC TRANSPORTZafar Iqbal Axoplasmic transport is the intracellular movement of cellular components required for the maintenance and normal physiological functioning of neuronal cells. This book provides an up to date reference for both established investigators as well as for those entering in the field.This volume describes the history and methods of the study of transport and the involvement of energy, ions, calmodulin, microtubules and other cellular components in transport. It also discusses the transport of polypeptides, lipids, nucleic acids, neutrotransmitter containing components and various other particles in nerve fibres. A significant portion of this book is devoted to axoplasmic transport, regeneration and the relevance of transport in neurotropic functions are described in the alst four chapters, followed by a discussion on the mechanism of axoplasmic transport. |
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accumulation actin action activity amino acids amount analysis anterograde appear associated axoplasmic transport binding Biochem block Brain Res Ca² Ca2+ calcium calmodulin Cell Biol cell body changes components concentration contain crush cytoplasm decrease demonstrated dependent diabetes distal distribution effect endings enzymes evidence experimental experiments fast axonal transport fast-transported Figure fraction function ganglion glucose glycoproteins glycosylation hypothyroidism incorporation increase indicated inhibition injection involved labeled localization mammalian material mechanism membrane microtubules molecules motor movement muscle nerve fibers nervous neurites Neurochem neurofilaments neurons Neurosci normal observed occur Ochs optic organelles particles peripheral Physiol possible preparation present proteins proximal rapid recently regenerating regions regulation reported retrograde transport role root sciatic nerve seen segments showed shown similar slow specific structure studies substance suggested synaptic synthesis terminals tissue tRNA vesicles vitro