Intracellular Regulation of Ion Channels
Martin Morad, Zalman Agus
Springer-Verlag, Jan 1, 1992 - Cellular control mechanisms - 251 pages
Understanding the molecular processes by which ionic channels are regulated is central to the understanding of cellular function. The book brings together and evaluates new ideas and experimental findings on these regulatory mechanisms. It is organized into three sections. The first deals with the diversity of K+ channels and their regulation, including structure-function and mechanistic studies. The second section covers the molecular understanding of Ca2+ channel function, its regulation and genetic manipulation. The third section treats the regulation of other types of channels, including Na+, Cl-, and If channels.
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K channel diversity
Regulation of voltageactivated K channels
Gating mechanisms of Shaker potassium channels
21 other sections not shown
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60 Intracellular Regulation Acad action potential adenylyl cyclase agonists Agus APD shortening arachidonic acid atrial Berlin Heidelberg 1992 Biol Birnbaumer block Ca2+ calcium channels calcium current cAMP cAMP-dependent phosphorylation cAMP-dependent protein kinase cardiac myocytes Catterall cellular channel activity Codina concentration cyclase cytoplasmic cytosolic delayed rectifier dependent depolarization DiFrancesco effects efflux frog function G protein glibenclamide Hartzell heart Hescheler hypoxia Ikar inactivation increase inhibition inhibitor intracellular Ion Channels Edited ischemia isoproterenol K+ channel KACh channel Kameyama KATP kinetics L-type mammalian mechanism membrane potential membrane-delimited modulation molecular Morad muscarinic Natl neurons Neurosci neurotransmitters outward current pacemaker pathway Pelzer Pflügers Arch phosphorylation Physiology pipette potassium channels potassium current prepulse pulses Purkinje fibers receptors Regulation of Ion RINm.5F sensitive Shaker skeletal muscle sodium channel solution Springer-Verlag Berlin Heidelberg subunit sulfonylureas Trautwein Tsien ventricular cells ventricular myocytes voltage voltage-dependent Yatani