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How It Really Happened
Receptor Binding and Probing
Purification and Structure
9 other sections not shown
3T3-L1 adipocytes Acad activity adipocytes affinity amino acid anti-insulin antibodies antigen Banting biochemical Biol biological brane cell membrane cell surface cell types cellular ceptor chapter Chem chloroquine coated pits decreased degradation diabetes mellitus disulfide bonds dose-response curves effects of insulin electrical endocytosis enzymes extract fibroblasts Figure Fm-I function glucose disposal glucose transport groups Houten hyperpolarization IGF-I IGFs increase incubated insulin action insulin binding insulin concentrations insulin receptor insulin resistance insulin stimulation insulin-induced insulinlike interaction internalization intracellular Jarett kinase labeled ligand liver lymphocyte lysosomes mechanism mediator membrane potential metabolism microclustering molecular weight molecule Natl normal obese observed Olefsky oxytocin pancreatic patients peptide hormones phospholipid phosphorylation Physiol plasma membrane polypeptide postreceptor defect Proc proreceptor protein pyruvate dehydrogenase recep receptor sites regulation residues response role sequence specific structure studies subunits sulin synthesis T-cell T-lymphocyte target tissues tion type II diabetes tyrosine uptake vesicles Zierler