Insulin: Its Receptor and DiabetesMorley D. Hollenberg, Julia McFarlane Diabetes Research Unit (University of Calgary) |
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Page 111
... . Investigations have been performed to help determine the mechan- ism responsible for holding the groups of adipocyte insulin receptors Receptor sites per group ( % of total occupied receptor Tissue - Specific Variations 111.
... . Investigations have been performed to help determine the mechan- ism responsible for holding the groups of adipocyte insulin receptors Receptor sites per group ( % of total occupied receptor Tissue - Specific Variations 111.
Page 125
Its Receptor and Diabetes Morley D. Hollenberg, Julia McFarlane Diabetes Research Unit (University of Calgary). of insulin receptors was found to be similar to the IM - 9 lymphocyte and 3T3 - L1 adipocyte . Most of the receptor sites ...
Its Receptor and Diabetes Morley D. Hollenberg, Julia McFarlane Diabetes Research Unit (University of Calgary). of insulin receptors was found to be similar to the IM - 9 lymphocyte and 3T3 - L1 adipocyte . Most of the receptor sites ...
Page 129
... receptors was not occurring . The entire plasma membrane was divided into three structural components , pinocytotic invaginations , coated pits , and the remainder of the membrane . An analysis of the concentration of re- ceptor sites ...
... receptors was not occurring . The entire plasma membrane was divided into three structural components , pinocytotic invaginations , coated pits , and the remainder of the membrane . An analysis of the concentration of re- ceptor sites ...
Contents
How It Really Happened | 7 |
Receptor Binding and Probing | 21 |
Purification and Structure | 39 |
Copyright | |
9 other sections not shown
Common terms and phrases
3T3-L1 adipocytes Acad activity adipocytes affinity amino acid anti-insulin antibodies antigen Banting biochemical Biol biological brane cell membrane cell surface cell types cellular ceptor chapter Chem chloroquine coated pits decreased degradation diabetes mellitus disulfide bonds dose-response curves effects of insulin electrical endocytosis enzymes extract fibroblasts Figure Fm-I function glucose disposal glucose transport groups Houten hyperpolarization IGF-I IGFs increase incubated insulin action insulin binding insulin concentrations insulin receptor insulin resistance insulin-induced insulin-receptor complex insulinlike interaction internalization intracellular Jarett kinase labeled ligand liver lymphocyte lysosomes mechanism mediator membrane potential metabolism molecular weight molecule Natl normal obese observed Olefsky oxytocin pancreatic patients peptide hormones phospholipid phosphorylation Physiol plasma membrane polypeptide postreceptor defect Proc proreceptor protein pyruvate dehydrogenase recep receptor sites regulation residues response role sequence specific stimulation structure studies subunits sulin synthesis T-cell T-lymphocyte target tissues tion type II diabetes tyrosine uptake vesicles Zierler