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5-point scale activity aerobic exercise aerobic training aerobic training program amitriptyline Angina pectoris Applied Physiology Astrand average biofeedback blood brain catecholamines cerebral changes chronic clinical cycle associated headaches Dalessio decrease drugs effort migraine emotional stress epinephrine ergotamine ergotamine tartrate exercise training factors five individuals frequency and intensity headache frequency headache intensity heart rate homeostasis hormonal hypocapnia increase individuals with migraine intensity of headache intensity was rated Journal of Applied l=mild 5=severe l0 weeks Lance maximal oxygen uptake Mean Mean Medical menstrual cycle associated metabolic methysergide migraine attacks migraine headache migraine prophylaxis migraine sufferers migraine therapy muscle Neurology nondrug norepinephrine Number pain person physical training physiological plasma platelet platelet aggregation post-treatment predicted maximal oxygen Pretraining propanolol prophylaxis prostaglandin reduction in headache reported response running self-care practices serotonin serum seven women Sicuteri side effects submaximal training period trigger variable vasoconstriction week of training Weekly Headache Frequency weeks of aerobic