Hans Marquardt, Siegfried G. Schäfer, Roger O. McClellan, Frank Welsch
Academic Press, Oct 5, 1999 - Medical - 1330 pages
Toxicology is a comprehensive text for researchers and graduate students in toxicology and public health. It addresses every aspect of the field, starting with the fundamentals and incorporating such areas as organ toxicology, applications, and environmental toxicology. In addition to covering the traditional subject matter of toxicology, special emphasis has been placed on recent areas of interest, such as risk assessment, apoptosis, and methodical developments.
* Comprehensive text, covering all aspects of the field of toxicology
* Analyzes the importance of toxicokinetics and metabolism as well as cellular targets for the mechanisms of toxic effects
* Identifies the various classes of chemical compounds responsible for the toxic effects
* Describes the approaches and methods used by various disciplines which investigate toxic effects and their prevention
* Adapted from a very successful German text, this edition is completely revised and expanded
* The text is well illustrated with diagrams, charts, and tables
What people are saying - Write a review
We haven't found any reviews in the usual places.
absorption acid action activity acute agents alcohol animals antigen apoptosis aromatic benzene binding blood cancer carcinogenesis carcinogenic cause cell death cellular chemical chronic clearance complex compounds concentration cytochrome cytochrome P450 cytokines cytotoxic damage deﬁned detected disease dose drug effects enzyme estrogen ethanol example excreted experimental exposure factors ﬁrst ﬂow formation function gene genetic genotoxic glomerular glutathione half-life hormones humans hydrocarbons immune system increased induced inﬂuence inhalation inhibition initiated interactions kidney kinetics lead lesions levels lipid liver lung malformations mechanisms membrane metabolism metabolites mice mixtures molecules mutagenic mutation necrosis nephrotoxicity organ oxidative oxygen pathway peroxide pesticides plasma poisoning polycyclic polycyclic aromatic hydrocarbons potential produce proliferation protein radicals rats reactions reactive receptor renal response rodents role signiﬁcant skin species speciﬁc studies substances substrate T-cells target teratogenic thalidomide tion tissue toxicity Toxicol toxicology transgenic tumor promoters vitro vivo xenobiotics