Anti-rheumatic DrugsE. C. Huskisson |
Contents
THE MODE OF ACTION OF ANTIINFLAMMATORY DRUGS WHICH PREVENT | 11 |
CLINICALLY SIGNIFICANT DRUG INTERACTIONS WITH ANTIRHEUMATIC DRUGS 32 | 37 |
ASPIRIN AND THE SALICYLATES 55 | 55 |
Copyright | |
34 other sections not shown
Common terms and phrases
acid action activity acute administration adverse agents analgesic anti-inflammatory appears aspirin associated blood cause cells cent changes chronic clinical Clinical Pharmacology compared comparison compounds concentrations controlled daily demonstrated developed diclofenac sodium diflunisal disease dosage dose double-blind drugs efficacy et al evidence excretion fenclofenac Figure four function gastrointestinal given gold half-life human Huskisson ibuprofen improvement incidence increased indicated indomethacin indoprofen inflammation inflammatory inhibition injection interaction International joint Journal less levamisole levels measured Medical Medicine mg/kg months naproxen normal observed occur oral orgotein pain patients penicillamine period phenylbutazone piroxicam placebo plasma platelet potent produced prostaglandin rats reactions receiving reduced renal reported Research response rheumatoid arthritis Rheumatology salicylate serum severe showed shown side effects significant significantly similar single sodium subjects sulindac symptoms synovial fluid Table tests therapeutic therapy tion tissue tolerated tolmetin toxicity treated treatment trial weeks