Anti-rheumatic DrugsE. C. Huskisson |
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Page 329
... orgotein at dose levels from 0.05 to 0.5 mg / ml of medium . Even at the highest doses tested , the antiviral effects of orgotein were limited to herpes simplex and parainfluenza - 3 virus ( Drew et al , 1973 , unpublished data ) . In ...
... orgotein at dose levels from 0.05 to 0.5 mg / ml of medium . Even at the highest doses tested , the antiviral effects of orgotein were limited to herpes simplex and parainfluenza - 3 virus ( Drew et al , 1973 , unpublished data ) . In ...
Page 332
... orgotein , either by the isoelectric focusing - SOD test or by radioimmunoassay . Drug Interactions In a typical screen , orgotein in doses up to 10 mg / ml was found not to inter- fere with the antibacterial efficacy of antibiotics and ...
... orgotein , either by the isoelectric focusing - SOD test or by radioimmunoassay . Drug Interactions In a typical screen , orgotein in doses up to 10 mg / ml was found not to inter- fere with the antibacterial efficacy of antibiotics and ...
Page 341
... orgotein group ( 4 mg / injection ) , the degree of improvement vs gold decreased as the frequency of orgotein injections was reduced , indicating a dose - rate dependence for the orgotein response ... orgotein in RA patients “ ORGOTEIN 341.
... orgotein group ( 4 mg / injection ) , the degree of improvement vs gold decreased as the frequency of orgotein injections was reduced , indicating a dose - rate dependence for the orgotein response ... orgotein in RA patients “ ORGOTEIN 341.
Contents
THE MODE OF ACTION OF ANTIINFLAMMATORY DRUGS WHICH PREVENT | 11 |
CLINICALLY SIGNIFICANT DRUG INTERACTIONS WITH ANTIRHEUMATIC DRUGS 32 | 37 |
ASPIRIN AND THE SALICYLATES 55 | 55 |
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acid action activity acute administration adverse agents analgesic anti-inflammatory appears aspirin associated blood cause cells cent changes chronic clinical Clinical Pharmacology compared comparison compounds concentrations controlled daily demonstrated developed diclofenac sodium diflunisal disease dosage dose double-blind drugs efficacy et al evidence excretion fenclofenac Figure four function gastrointestinal given gold half-life human Huskisson ibuprofen improvement incidence increased indicated indomethacin indoprofen inflammation inflammatory inhibition injection interaction International joint Journal less levamisole levels measured Medical Medicine mg/kg months naproxen normal observed occur oral orgotein pain patients penicillamine period phenylbutazone piroxicam placebo plasma platelet potent produced prostaglandin rats reactions receiving reduced renal reported Research response rheumatoid arthritis Rheumatology salicylate serum severe showed shown side effects significant significantly similar single sodium subjects sulindac symptoms synovial fluid Table tests therapeutic therapy tion tissue tolerated tolmetin toxicity treated treatment trial weeks