Hepatology: A Textbook of Liver Disease, Volume 1
David Zakim, Thomas D. Boyer
Saunders, 1990 - Liver - 1568 pages
This text presents both comprehensive coverage of normal hepatic physiology and cell biology and all aspects of clinical liver disease. Topics covered include new information on viral hepatitis, connective tissue metabolism, and surgical management of liver tumours.
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Toxic Injury to the Liver
Chemical Mechanisms in DrugInduced Liver
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abnormalities Acad Sci USA Acta activity acute ALA synthase albumin amino acids bile acid bile salts biliary bilirubin binding Biochem Biochim Biophys Biol Chem biosynthesis blood flow canalicular catalyzed Cell Biol cent cholestasis cholesterol circulation cirrhosis clathrin clearance Clin Invest collagen concentration conjugated cytochrome P450 cytoplasmic decreased drug duct effects enzyme esters excretion fatty acids function gallbladder Gastroenterology Gilbert's syndrome glucose glycogen glycoproteins Golgi growth factor heme hepatic arterial hepatocytes hormones hyperbilirubinemia increase induced inhibition insulin intestinal intracellular isolated kinase kinetics ligand lipid lipoprotein liver cells liver disease lysosomal mechanism metabolism microsomal molecule mRNA Natl Acad Sci normal oxidation pathway patients perfused pharmacokinetics Pharmacol Physiol pigment plasma membrane porphyria portal Proc Natl Acad protein protoporphyrin rat hepatocytes rat liver reaction receptor regulation role secretion secretory serum sinusoidal structure studies substrate tion tissue transferrin transport unconjugated uptake vesicles vitamin vitro vivo VLDL