Developmental Neuropathology

Front Cover
Springer Science & Business Media, Dec 6, 2012 - Medical - 524 pages
The present text was envisioned as a supplement to eXlstmg texts on human neuropathology, covering only those aspects of pediatric neuropathol ogy which pertain to and are peculiar of the immature nervous system. No coverage-or only brief comment-is given to diseases commonly found in adults which may, on occasion, occur in childhood or infancy as well. The subject matter is divided into three main categories: 1. The "acquired" lesions dating to the fetal, perinatal or early postnatal periods, 2. the malformations, and 3. the heritable metabolic defects. The first 6 chapters (2-7) are reserved to the lesions most intimately linked to the circumstances of birth. There is some inherent ambiguity in distinguishing between "acquired" lesions and malformations, as, indeed, no sharp distinction can be made between one and the other. Many malformations result from diseases acquired during fetal life and their peculiarity resides in the fact that the organ becomes affected before its development terminates and in such a way that its subsequent development becomes deranged or partly abrogated. A variety of causes acting at the same developmental period or over a common pathogenetic mechanism may produce the same type of derangement, including chemical, physical, infectious or genetic factors, as pointed out repeatedly in the text. Consequently, the definition of a malformation, as differing from an "acquired" residual lesion was made dependant on evidence for the derangement of developmental pro cesses subsequent to the acquisition of the disease.
 

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

Gross and Microscopic Development of the Central Nervous System
1
White Matter 6 Periventricular Matrix Tissue 7 Myelin Forma
13
First Part Acquired Lesions in Newborns and Infants
24
Cerebral Lesions from Physical Trauma
37
Periventricular Infarcts
44
Perinatal Lesions of Cerebral and Cerebellar Cortex
57
Lesions of Basal Ganglia Brain Stem and Cord
64
Kernicterus Bilirubin Encephalopathy
75
The ArnoldChiari Malformation ClelandChiari Malformation
253
Ventral Dysraphic and Various Sacral Lesions
266
Disturbances in the Bulk Growth of Nervous Tissue
271
Dysplasias of Cerebral Hemispheric Organization
280
Dysplasias of Cerebral Cortex
297
Dysplasia of Cerebellar Hemispheric Organization 31 4
323
Dysplasias of Brain Stem and Spinal Cord
339
Dysplasias in Chromosome Disorders
351

Spongy GlioNeuronal Dystrophy
93
Porencephaly Hydranencephaly Multilocular Cystic Encephalopathy
102
Arterial Occlusive Disease in Infancy
122
Thrombosis of Intracranial Sinus and Veins
135
Cerebral Lesions in Congenital Cardiac Disease
144
CranioCerebral Trauma in Infancy
150
Leptomeningitis in Newborns and Infants
166
Meningoencephalitic Processes in the Perinatal Period
178
Subdural Hematomas Hygromas and Effusions
187
Meningeal Cysts
196
HydrocephalusBasic Concepts and General Pathology
203
HydrocephalusSpecial Pathology
214
Second Part Malformations
230
Spina Bifida and Related Spinal Lesions
240
Dysplasias of Cerebral Vasculature
357
Third Part Metabolic Diseases
368
Sphingolipidoses
385
Ceroid Lipofuscinosis Miscellaneous Lipidoses
408
Metachromatic Leukodystrophy Sulfatase A Deficiency and Multiple Sulfatase
423
Globoid Cell Leukodystrophy
433
AdrenoLeukodystrophy and Its Relations to Schilder Disease
442
PelizaeusMerzbacher Disease Cockayne Syndrome and Related Conditions
449
Alexander Disease and Related Conditions
458
Spongy Degeneration of the Central Nervous System and Other Forms of Spongy
476
Diseases of Intermediary Metabolism
488
Appendix
505
Subject Index
519
Copyright

Other editions - View all

Common terms and phrases

Bibliographic information