Gastric Mucosal Protection: An Experimental Study on the Role of Endogenous and Exogenous Phospholipids |
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acute administration of indomethacin antrum apical arachidonic acid Axelson canine gastric chronic antral ulcers chronic ulcers control rats cytoprotection decreased dose Dunjić duodenum epithelial erosions ethanol evaluated exogenous phospholipids experimental expressed as meanąSEM fatty acids gastric barrier gastric mucosal barrier gastric mucosal blood gastric mucosal injury gastric mucosal lesions gastric phospholipids gastric ulcers Gastroenterology gastrointestinal tract greater curvature Hills BA hydrophobicity indomethacin indomethacin-treated rats induced injection of indomethacin intragastrically Lichtenberger LM lipids luminal Lund mechanism membrane mg/kg body weight mg/ml microvascular misoprostol mm˛ mucosal blood flow mucosal defense mucosal protection mucus mucus gel non-steroidal anti-inflammatory drugs parietal cells pectin phosphatidylcholine phospholipase A2 phospholipid content Physiol pretreatment prostaglandins protect the gastric protective capacity protective effect refed rats refeeding role Satoh Scand J Gastroenterol secretion Silen Slomiany small intestine stomach sucralfate surface mucous cells surface-active phospholipids synthesis Tarnawski tissue ulcer index ulcers in rats unsaturated