Chemistry and PharmacologyInternationally acclaimed for more than 40 years, this Series, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structure elucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, or various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Over the years, this Series has become the standard in natural product chemistry to which all other book series aspire. The Alkaloids: Chemistry and Pharmacology endures as an essential reference for all naturalproduct chemists and biologists who have an interest in alkaloids, their diversity, and their unique biological profile.
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Contents
Chapter 2 Alkaloids Containing Quinolinequinone and Quinolinequinoneimine Units | 79 |
Chapter 3 Biosynthesis of Terpenoid Indole Alkaloids in Catharanthus roseus Cells | 221 |
Chapter 4 Macrocyclic Peptide Alkaloids from Plants | 301 |
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Common terms and phrases
acetate acid AcOH ajmalicine aldehyde alkaloid biosynthesis alkaloid production amide amine analogs antitumor activity ascididemin astins biogenetic Biological Activity biosynthesis C-NMR catharanthine CDCl3 cell cultures Chem chloroform chorismate chromatography compound configuration conformation cyclization cyclopeptide alkaloid cystodytins cytotoxicity derivative diazaquinomycin discorhabdin elegans enzyme ester EtOH extract gave gelsemine gene geraniol H-NMR H3CO Heterocycles HMG-CoA inhibition intermediate isolated isomer KB cells ketone koumine lavendamycin M. H. Zenk metabolism methanol methoxy methyl ester mixture molecular OCH3 oxidation oxindole pathway peptide alkaloids phomazarin Phytochemistry Plant Cell Plant Physiol prianosin protein proton pyridine quinoline RA-V RA-VII reaction Reagents reflux reported RI-Me ring roseus cell Scheme secologanin Segetalin showed silica gel spectroscopic streptonigrin strictosidine structure elucidation tabersonine terpenoid terpenoid indole alkaloids Tetrahedron Lett total synthesis treatment tryptamine tryptophan UV MeOH Verpoorte vindoline X-ray yield