Retinoids, Part B: Cell Differentiation and Clinical Applications
John H. Law, Klaus Mosbach, Lester Packer, Anthony R. Means, Kivie Moldave, John N. Abelson, Sidney P. Colowick, Ludwig Brand, Harold W. Wyckoff, Michael L. Johnson, Nathan P. Kaplan, Melvin I. Simon, P. Michael Conn, Nathan Oram Kaplan, James F. Riordan, Finn Wold, Victor Ginsburg, John J. Langone, C. H.W. Hirs, James E. Dahlberg, Hans C. Rilling, Anthony San Pietro, Jacek J. Hawiger, David M.J. Lilley, Tony Hunter, Herbert Tabor, Norman J. Oppenheimer, Alexander N. Glazer, Bert L. Vallee, Serge N. Timasheff, Celia White Tabor, Thomas L. James, Bartholomew M. Sefton
Elsevier Science, 1971 - Medical - 681 pages
This volume contains a comprehensive collection of methods for the isolation of platelet membranes, subcellular organelles, the cytoskeleton, and for the assay and purification of platelet receptors.
* Platelets are cellular elements with the highest density of receptors per membrane surface area involved in binding of adhesive molecules, clotting, enzymes, and vasoactive amines
* Platelets are essential for the arrest of bleeding and for formation of intravascular thrombi contributing to heart attacks, strokes, and disseminated intravascular coagulation, and are involved in immune complex disease
* Platelets are useful for studying the processes of cell adhesion, neurotransmitter uptake, stimulus-response coupling, including signal transduction and secretion
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