A strategy for research in space biology and medicine in the new century
National Academy Press, 1998 - Medical - 276 pages
The Committee on Space Biology and Medicine reviewed and updated prior reports to suggest strategies for research in space biology and medicine based on information gathered since 1987. The report provides a review of biology and medicine that can be studied in the space environment, discusses the fundamental research issues and questions with space biology and medicine disciplines, identifies the most promising experimental challenges in those disciplines, evaluates the potential for space research to provide advances within each discipline, and prioritizes research topics to the extent feasible. Disciplines include sciences which study plant, animal, and human systems at the molecular, cellular, system, and whole-organism levels. The section about physiology, gravity, and space includes cell biology; developmental biology; plants, gravity, and space; sensorimotor integration; bone physiology; skeletal muscle; cardiovascular and pulmonary systems; endocrinology; and immunology. The section about additional space environment issues includes radiation hazards and behavioral issues. The final section examines setting priorities in research and programmatic and policy issues.
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PROGRAMMATIC AND POLICY ISSUES
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activity adaptation alterations animals Appl Arabidopsis assessment astronauts auxin Aviat Bain behavior and performance Biology and Medicine blood bone loss cardiovascular cell biology cells cellular changes circadian rhythms cosmonauts countermeasures crew members cytokines decreased determine dose Earth effects of microgravity effects of spaceflight endocrine experiments exposure flight fluid shifts function gene genetic gravitropism gravity vector ground-based hindlimb suspension hindlimb unloading hormone human immune system in-flight increased induced interactions interleukin investigators Konstantinova Krippendorf Leukocyte Biol levels long-duration missions measurements mechanisms metabolism microgravity molecular NASA orthostatic orthostatic intolerance osteoblasts particles Physiol physiological plants postflight preflight priority protein protons radiation rats Recommendations regulation response Riley risk sarcomere Science Sedlak sensory shuttle skeletal muscle Skylab Slocum SLS-1 and SLS-2 soleus soleus muscle Sonnenfeld Space Biology Space Environ space motion sickness Space Station spaceflight Spacelab specific stimulation Strategy stress studies tissue vestibular system weightlessness