The Physical Basis of Biochemistry: The Foundations of Molecular Biophysics

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Springer Science & Business Media, 1998 - Science - 567 pages
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The Physical Basis of Biochemistry is a rigorous, imaginative textbook that applies physical and chemical principles to understanding the bi ology of cells. The book features numerous problem sets and examples, clear illustrations, and extensive appendices that provide additional information on mathematics, physics and chemistry topics that support the text. The Physical Basis of Biochemistry is suitable for graduate and advanced undergraduate courses in physical biochemistry, biophysic al chemistry, and physical chemistry with application in the life scie nces. It will be welcomed by instructors seeking a text which combines a quantitative approach with a consistent biological perspective.
 

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Contents

Introduction to the Principles and Practice of Biophysical
3
Probability and Statistics
27
EnergyThe Prime Observable
43
Waves
68
Electrostatics
97
Electromagnetics
109
Quantum Mechanics
125
Chemical Principles
158
The Formation of the Cell
330
Constructing a Biological State Space
346
Macromolecules in Solution
361
Mapping Biochemical State Space
394
The Electrified Interface
415
Forces Across Membranes
427
Function and Action in State Space
439
Diffusion
445

Energetics and the First
175
Entropy
187
Which Way Is That System Going? The Gibbs Free Energy
208
Phase
228
Analysis of Structure
249
Microscopy
268
Scenic Overlook Backward and Forward
282
IonSolvent Interactions
300
IonIon Interactions
319
Conduction
455
Electrokinetic Phenomena
472
Chemical Kinetics
480
Enzymes and Electrons
498
Epilogue
516
The Centrifugal Force
526
uvriui lmalion of the Energy of Interaction Between Two Ions
534
rt uCc L Adiabalic and Nonadiabatic Transitions
541
iw
549

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Page 516 - Mechanism of long-distance electron transfer in proteins: Lessons from photosynthetic reaction centers.

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About the author (1998)

Peter R. Bergethon graduated from Williams College with honors in biology for research in neurocybernetics. He earned an M.D. from Jefferson Medical College and is board certified in internal medicine and neurology. and received NIH Physician-Scientist training in biophysical chemistry and completed fellowship training in EEG and neurophysiology. A classroom and clinical teacher for 25 years, he has taught biophysical chemistry, medical biochemistry and cognitive neuroscience serving as a Professor of Anatomy & Neurobiology and Biochemistry at Boston University School of Medicine and adjunct faculty in the departments of Neurology and in Bioengineering at Tufts University. He has written or contributed to over one hundred research papers and books including the SymmetryScience science education program.

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