Oxazine Derivatives as Analgesics |
Common terms and phrases
3-necked flask equipped absolute ethanol absolute ether amino acid ammonium hydroxide Anal analgesic Attempted Preparation B-methylaminoethanol benzene benzilic acid brown solution Caled Cels CH CH CH Chem Chlorohydrin collected and dried compound crystalline solid separated Cut Pressure Temperature cyclization dilute Diphenylacetonitrile diphenylbromoacetic acid Diphenylbromoacetonitrile dropping funnel drugs dry benzene ethyl diphenylchloroacetate ethylene bromohydrin ethylene oxide filtered filtrate flask was placed form a picrate free amine gave a negative glacial acetic acid HOCH hydrogen bromide hydrogen bromide gas hydrogen chloride hydrogen chloride gas isopropyl alcohol Methadone methylamine methylamine hydrochloride methylaminodiphenylacetic acid minutes mixture was refluxed mole morphine negative test oxazine phosphorus oxychloride reaction mixture recrystallized refluxed round-bottom flask round-bottom flask fitted sample was recrystallized saturated set overnight solid was collected solu solution was refluxed starting material stirrer sulfuric acid synthesized test for halogen test for nitrogen thionyl chloride tube white crystalline solid white solid separated yellow liquid